Inhibition of N-Methyl-N-Nitrosourea-Induced Mammary Tumors by Nutrient Synergy – A Novel Anti-Cancer Agent

Roomi MW, Roomi NW, Ivanov V, Niedzwiecki A, Rath M

Presented at: 
95th Annual Meeting of American Association for Cancer Research, Orlando, FL, March 27-31, 2004.

Published in: 
95th Annual Meeting of American Association for Cancer Research Proceedings, 45:881, March 2004.


Incidence and mortality from breast cancer in women, the third most prevalent cancer worldwide, is steadily increasing, especially in developed societies. This study examined the synergistic effect of a specific formulation of nutrients containing lysine, proline, ascorbic acid and green tea extract on the growth of mammary tumors induced in 50-day-old female Sprague-Dawley rats by the carcinogen N-methyl-N-nitrosourea (MNU). Nutrient Synergy significantly inhibited the incidence, as well as the growth, of MNU-induced mammary tumors, indicating that it has strong potential as a useful therapeutic regimen for inhibiting breast cancer development.