Scientific Presentations

Influenza

Micronutrients in the global fight against influenza

Jariwalla RJ, Roomi MW, Kalinovsky T, Rath M, Niedzwiecki A
In: Global View of the Fight Against Influenza, edited by Petar Mitrasinovic, Nova Publishers, 2009

Abstract:
Influenza remains a major health threat among infectious diseases, affecting a fifth of the world’s population. Current vaccines and drugs have limited efficacy and there is an urgent need for effective therapies. Influenza virus A not only infects susceptible (alveolar) cells in the lungs, but also manifests in extrapulmonary areas, which require basement membrane disruption by matrix metalloproteinases (MMPs) capable of degrading collagen type IV.

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Micronutrients and Nutrient Synergy in Immunodeficiency and Infectious Disease

 

Jariwalla RJ, Niedzwiecki A, Rath M
Botanical Medicine in Clinical Practice, eds. Preedy VR and Watson RR., Chapter 23, 2008

Abstract:
Good nutrition is vital to immune function and disease resistance. Conversely poor nutritional status or malnutrition can lower immunity and predispose to infection. Nutritional deficiencies are common in disorders of the immune system and in viral and bacterial infections. Experimental studies conducted to date with micronutrients have revealed beneficial effects with the potential to combat both immunodeficiency disease and microbial infection.

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Inhibition of cellular invasive parameters in influenza A virus-infected MDCK and Vero cells by a nutrient mixture

M.W. Roomi, R.J. Jariwalla, T. Kalinovsky, N. Roomi, A. Niedzwiecki, M. Rath
BioFactors 2008; 33: 61-75

Influenza, a long-standing common infection, poses a serious health problem causing significant morbidity and mortality, and imposing substantial economic costs. To date there are no effective antiviral therapies. A unique nutrient mixture (NM), containing lysine, proline, ascorbic acid, green tea extract, N-acetyl cysteine and selenium among other micro nutrients, has been shown to exert a wide range of biochemical and pharmacological effects, among them anti-carcinogenic and anti-atherogenic activity both in vitro and in vivo.

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Effects of a nutrient mixture on infectious properties of the highly pathogenic strain of avian influenza virus A/H5N1

P.G. Deryabin, D.K. Lvov, A.G. Botikov, V. Ivanov, T. Kalinovsky, A. Niedzwiecki, M. Rath 
Biofactors 2008, 33(2): 85-97

Abstract:
Numerous outbreaks of avian influenza virus infection (A/H5N1) have occurred recently, infecting domestic birds, chicken and ducks. The possibility of the emergence of a new strain of influenza virus capable of causing a pandemic in humans is high and no vaccine effective against such a strain currently exists. A unique nutrient mixture (NM), containing lysine, proline, ascorbic acid, green tea extract, N-acetyl cysteine, selenium among other micro nutrients, has been shown to exert a wide range of biochemical and pharmacological effects, including an inhibitory effect on replication of influenza virus and HIV.

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Allevation of histopathological effects of avian influenza virus by a specific nutrient synergy

Babour EK, Rayya EG, Shaib H, El Hakim RG, Niedzwiekci A, Abdel Nour AM, Harakeh S, Rath MIntern 
The International Journal of Applied Research in Veterinary Medicine 2007; 5(1): 9-16

Abstract:
This study focused on the effects of a nutrient mixture containing ascorbic acid, lysine, proline, green tea extract and other micronutrients in alleviating the histopathologic effects of avian influenza virus.

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