Scientific Presentations


Essential nutrients suppress inflammation by modulating key inflammatory gene expression

V. Ivanov, J. Cha, S. Ivanova, T. Kalinofsky, M.W. Roomi, M. Rath, A. Niedzwiecki
International Journal of Molecular Medicine 2008; 22(6): 731-741

We investigated the effects of a nutrient mixture (NM) including ascorbic acid, quercetin, naringenin, hesperetin, tea catechins, lysine, proline, arginine and N-acetyl cysteine in experimental in-vivo and in-vitro inflammation triggered by bacterial lipopolysaccharide (LPS). BALB/c mice (n=36) were supplemented with NM (200 mg/kg BW) or ibuprofen (20 mg/kg BW) for two weeks. Blood plasma, collected three hours after a single intraperitoneal injection with LPS (1 mg/kg BW), was analyzed with 14 cytokine microarray.

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