A. Goc, W. Sumera, M. Rath, A. Niedzwiecki

PLoS ONE 18(8): e0290904. https://doi.org/10.1371/journal.pone.0290904

Abstract:
The ongoing rise in antibiotic resistance, and a waning of the introduction of new antibiotics, has resulted in limited treatment options for bacterial infections, including these caused by methicillin-resistant Staphylococcus aureus, leaving the world in a post-antibiotic era.

Read more: Inhibition of α-hemolysin activity of Staphylococcus aureus by theaflavin 3,3’-digallate

A. Goc, W. Sumera, A. Niedzwiecki, M. Rath

PLOS ONE | https://doi.org/10.1371/journal.pone.0214763 April, 2019

Abstract: In the search for novel agents against oral pathogens in their planktonic and biofilm form, we have focused our attention on 10-undecynoic acid as the representative of the acetylenic fatty acids.…

Read more: 10-undecynoic acid is a new anti-adherent agent killing biofilm of oral Streptococcus spp.

Barbour EK, Mastori FA, Shaib HA, Yaghi RH, Tayeb IT, Sleiman FT, Kassaify ZG, Sawaya RK, Abdel Nour AM, Sabra AH, Harakeh S, Rath M
The International Journal of Applied Research in Veterinary Medicine 2009; 7(1): 43-49

Abstract:
The main objective of this study was to evaluate the efficacy of a nutrient mixture (NS) containing lysine, proline, green tea extract, ascorbic acid and other micronutrients in alleviating the pathologic effects in broilers challenged with a high or low dose of E. coli following a primary challenge with H9N2 avian influenza virus. Six groups of 19 broilers each were treated as follows.…

Read more: Efficacy of a nutrient synergy against colibacillosis in poultry

Barbour EK, Mastori FA, Abdel Nour AM, Shaib HA, Jaber LS, Yaghi RH, Sabra A, Sleiman FT, Sawaya RK, Niedzwiecki A, Tayeb IT, Kassaify ZG, Rath M, Harakeh S, Barbour KE
Veterinaria Italiana 2009; 45(2): 317 – 322.

Abstract:
Primary infection by low pathogenic avian influenza (LPAI) predisposes poultry for secondary infection by Escherichia coli, leading to significant economic losses. Future research in control of this ailment requires the establishment of a successfully controlled challenge by avian influenza virus (AIV)/E.coli. Six groups of broilers (6 birds/group) were included for the standardization of the controlled challenge by AIV/E.coli.…

Read more: Standardization of a new model of H9N2/escherichia coli challenge in broilers in Lebanon

Vadim Ivanov1, Evgeniy E. Efremov2, Boris V. Novikov3, Vladimir M. Balyshev3, Sodnom Zh. Tsibanov3, Tatiana Kalinovsky1, Denis V. Kolbasov3, Aleksandra Niedzwiecki1, Matthias Rath1.
1, Dr Rath Research Institute BV, 1260 Memorex Drive, Santa Clara, CA, USA
2, Cardiology Research Center, 121552 Moscow, Russia.
3, National Research Institute for Veterinary Virology and Microbiology, 601120, Pokrov, Russia
Molecular Medicine Reports 2011, 4:395-401

Abstract:
Periodic outbreaks of African Swine Fever Virus (ASFV) infection around the world threaten local populations of domestic pigs with lethal disease and provide grounds for pandemic spread. Effective vaccination might bring this threat under control. We investigated the effectiveness of select peptides mimicking viral protein in raising a protective immune response. Forty six synthetic peptides were based on the analysis of the complete nucleotide sequence of ASFV and tested for immunogenicity in mice. The seventeen best immune response-inducing peptide candidates were selected for further investigation.…

Read more: Vaccination with Viral Protein-Mimicking Peptides Postpones Mortality in Domestic Pigs Infected by African Swine Fever Virus