Roomi MW, Ivanov V, Niedzwiecki A, Rath M
AACR-NCI-EORTC International Conference on Molecular Targets and Cancer, Boston, November 17-21, 2003.
Program Proceedings of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer, p. 165, Abstract #B196.
Cancer of the pancreas is a highly lethal disease with the poorest likelihood of survival among all major malignancies; metastasis is associated with more than 80% of the cases. This study demonstrated significant inhibition of the metastatic parameters of MMP expression, invasion, and angiogenesis, suggesting NS is an excellent candidate for therapeutic use in the treatment of pancreatic cancer.