Winning the Global Fight Against Cancer: the Nutrient Synergy Approach

M.W. Roomi, N.W. Roomi, T. Kalinovsky, M. Rath and A. Niedzwiecki
Dr. Rath Research Institute, Oncology Division, 1260 Memorex Drive, Santa Clara, CA

Presented at: 
International Conference on Nutritional Medicine, Health and Wellness, Kerala, India, June 7-8, 2012.

Published in: 
Proceedings of the International Conference NUWELL, Department of Zoology, St. Teresa College and University Grant Commission, New Delhi, 110002, 2012, pp 11-23.

 

Abstract

Consumption of plant-based diets has been shown to have a beneficial effect on cancer prevention and development. We have developed a combination of micronutrients containing lysine, proline, ascorbic acid and green tea extract (NM) that act synergistically to inhibit cancer development and its metastasis by strengthening collagen and connective tissues. NM has exhibited anticancer activity in vitro and in vivo in a number of cancer cell lines from various organ malignancies. In vitro studies demonstrated the effectiveness of NM in inhibition of cell proliferation, invasion, migration, MMPs, u-PA, angiogenesis, and up regulation of TIMPs and induction of apoptosis. In vivo, utilizing xenografts, NM significantly reduced the tumor size and tumor burden. NM also inhibited the growth of chemically-induced tumors in breast, skin and lung. Many cancers are often diagnosed at a later stage when metastasis has occurred, and standard treatment has failed to control its progress. Our studies on pulmonary, hepatic, testicular and peritoneal metastasis, using a mouse model, demonstrated significant reduction with NM treatment. Our results suggest that NM is an excellent candidate for therapeutic use in the treatment of a wide variety of cancers by inhibiting critical parameters such as proliferation, invasion, metastasis, and angiogenesis and by inducing apoptosis.

Comment

We have developed a combination of micronutrients containing lysine, proline, ascorbic acid and green tea extract (NM) that act synergistically to inhibit cancer development and its metastasis by strengthening collagen and connective tissues. Our results suggest that NM is an excellent candidate for therapeutic use in the treatment of a wide variety of cancers by inhibiting critical parameters such as proliferation, invasion, metastasis, and angiogenesis and by inducing apoptosis.


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