In vitro evaluation of antibacterial activity of phytochemicals and micronutrients against Borrelia burgdorferi and Borrelia garinii

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CONCLUSIONS:  The most effective antimicrobial compounds against all morphological forms of the two tested Borrelia sp. were baicalein and monolaurin. This might indicate that the presence of fatty acid and phenyl groups is important for comprehensive antibacterial activity. SIGNIFICANCE AND IMPACT OF THE STUDY:  This study reveals the potential of phytochemicals as an important tool in the fight against the species of Borrelia causing Lyme diseases. 

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Key Words:
Borrelia sp., biofilm, cysts, spirochetes, phytochemicals, Lyme disease, Borrelia burgdorferi

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