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21. A Unique Nutrient Mixture Suppresses Ovarian Cancer Growth Of A-2780 By Inhibiting Invasion And MMP-9 Secretion
(Scientific Presentations: Cancer)
... zymography, invasion through Matrigel and morphology by H&E staining. All control mice developed large ovarian tumors, whereas 5 out of 6 mice in the EPQ group developed no tumors, and one, a small tumor. ...
Created on 04 April 2015
22. Inhibitory Effects of Ascorbic Acid, Proline, and Lysine Supplementation on Matrigel Invasion by Human Breast Cancer Cells MDA-MB-231
(Scientific Presentations: Cancer)
...   Comment The results from this study demonstrated that while an individual nutrient, such as ascorbic acid, can inhibit the invasion of cancer cells through Matrigel (a model for extracellular matrix), ...
Created on 04 April 2015
23. Matrix Metalloproteinase-2 Inhibition and Invasion Potential in Human Chondrocytes by Nutrient Synergy – A Specific Mixture of Nutrients Containing Lysine, Proline, Ascorbic Acid and Epigallocatechin  ...
(Scientific Presentations: Cancer)
Roomi MW, Ivanov V, Netke SP, Niedzwiecki A, Rath M Presented at:  American Association of Cancer Research Special Conference in Cancer Research: Proteases, Extracellular Matrix and Cancer, Hilton Head ...
Created on 04 April 2015
24. Nutrient Synergy – A Specific Formulation of Nutrients Containing Lysine, Proline, Ascorbic Acid, and Epigallocatechin Gallate Inhibits Matrix Metalloproteinases Activity and Invasion Potential of Human ...
(Scientific Presentations: Cancer)
... acid, lysine, proline, and epigallocatechin gallate significantly inhibited the metastasis potential of human melanoma, breast and liver cancer cells by inhibiting the expression of MMPs and Matrigel invasion, ...
Created on 04 April 2015
25. Inhibitory Effect of Nutrient Synergy, a Specific Formulation of Nutrients Containing Lysine, Proline, Ascorbic Acid, and Epigallocatechin Gallate, on Matrix Metalloproteinase Activity and Invasion of ...
(Scientific Presentations: Cancer)
... ascorbic acid, and epigallocatechin gallate, significantly inhibited the expression of both MMP-2 and MMP-9, and the invasion of human fibrosarcoma HT-1080 cells through Matrigel in a dose dependent fashion, ...
Created on 04 April 2015
26. Nutrition Synergy Inhibits MMP Expression and Invasion Potential of Human Lung Carcinoma Cell Line A-549
(Scientific Presentations: Cancer)
... diagnosed in the United States, has one of the lowest survival rates of any cancer due to a high metastatic rate and poor results with standard treatment regimens. There is compelling evidence that invasion ...
Created on 03 April 2015
27. Nutrient Synergy - an Important Inhibitor of MMP-2 Expression and Invasion by Human Ovarian Cancer Cell Line SK-OV-3
(Scientific Presentations: Cancer)
... cancer cell invasive potential. Our results demonstrated complete inhibition of MMP-2 expression at 50 mg/ml and of Matrigel invasion at 1000 mg/ml. These findings are significant as they suggest that ...
Created on 03 April 2015
28. Suppression of Human Rheumatoid Synovial Fibroblast MMP-2 Expression and Marix Invasion by Nutrient Synergy
(Scientific Presentations: Cancer)
... in synovial membranes and have been implicated in synovial tissue invasion into adjacent cartilage and bone. Standard anti- arthritic drugs, used for prolonged periods, have been associated with serious ...
Created on 03 April 2015
29. Suppression of MMP Expression and Invasion of Human Cervical Cancer Cell Lines Hela and DoTc2 4510 by Nutrients
(Scientific Presentations: Cancer)
... leads to 30% to 40% invasion within ten years. We studied the synergistic effect of a unique nutrient formulation containing lysine, proline, arginine, ascorbic acid, and epigallocatechin gallate on metastatic ...
Created on 03 April 2015
30. Inhibition of Cell Invasion and MMP Production by a Nutrient Mixture in Malignant Liposarcoma Cell Line SW-872
(Scientific Presentations: Cancer)
... survival rate of patients with deep high-grade liposarcoma is less than 50%. Extracellular matrix (ECM) matrix metalloproteinases (MMPs) produced by tumor and stromal cells play a key role in tumor invasion ...
Created on 03 April 2015
31. Inhibition of Malignant Mesothelioma Cell Matrix Metalloproteinase Production and Invasion by a Novel Nutrient Supplement
(Scientific Presentations: Cancer)
... and nearly universal mortality. Extracellular matrix (ECM) matrix metalloproteinases (MMPs) produced by tumor and stromal cells play a key role in tumor invasion and metastasis. The nutrient mixture (NS) ...
Created on 03 April 2015
32. Novel Anticarcinogenic Effect of a Nutrient Mixture: Inhibition of MMPs, Invasion and Growth of Human Rhabdomyosarcoma in vitro
(Scientific Presentations: Cancer)
... on various cancer cell lines, on MMP expression, invasion and growth of pediatric rhabdomyosarcoma. Matrix metalloproteinases (MMPs) play a crucial role in tumor cell invasion, metastasis and angiogenesis, ...
Created on 03 April 2015
33. Down Regulation of Matrix Metalloproteinases and Inhibition of Cell Invasion by a Novel Nutrient Mixture in Human FA Fibroblast Cell Lines: in vitro Study
(Scientific Presentations: Cancer)
... tumor invasion and metastasis. Our in vitro studies demonstrated that the nutrient mixture (NM) of ascorbic acid, lysine, proline, and green tea extract inhibited FA cell MMP expression and invasion - ...
Created on 03 April 2015
34. A Novel Nutrient Mixture as an Antileukemic Agent with Matrix Metalloproteinase and Invasion Inhibitory Activities
(Scientific Presentations: Cancer)
... leukemia cell HL-60 proliferation, MMP activity, and invasion through Matrigel in vitro. Our results are significant as they indicate that this nutrient mixture is a promising non-toxic therapeutic agent ...
Created on 03 April 2015
35. Inhibition of MMP Activity and Cell Invasion by a Novel Nutrient Mixture on Glioma Cell Line A-172: in vitro Study
(Scientific Presentations: Cancer)
... depending upon treatment regimens, mainly due to invasion into the surrounding brain. A unique non-toxic nutrient mixture (NM) consisting of lysine, proline, ascorbic acid and green tea extract, shown ...
Created on 03 April 2015
36. Inhibitory Effect of a Novel Nutrient Mixture on MMP Secretion and Invasion on Human Thyroid Cancer Cell Line SW 579: In Vitro Study
(Scientific Presentations: Cancer)
... a number of cancer cell lines. Objective:  We investigated the effect of NM on human thyroid cancer cell SW 579 for viability, MMP secretion, invasion and morphology. Methods: Human thyroid cancer cell ...
Created on 03 April 2015
37. Inhibition of Hemangioendothelioma In Vivo and Invasion and Growth In Vitro by a Unique Nutrient Mixture
(Scientific Presentations: Cancer)
... viability, MMP secretion, invasion and morphology. Methods:  Athymic nude mice, 5-6 weeks old, were inoculated with 3x106 EOMA cells (ATCC) subcutaneously and randomly divided into two groups; group ...
Created on 03 April 2015
38. In Vitro Inhibition of MMPS, Invasion and Growth of Human Fanca and Fancc Lymphoblasts by a Unique Nutrient Mixture
(Scientific Presentations: Cancer)
... tumor invasion and metastasis. Biological agents that prevent extracellular matrix (ECM) degradation by MMPs have been shown to be promising therapeutic approaches to cancer. A nutrient mixture (NM) containing ...
Created on 03 April 2015
39. Marked Inhibition of Tumor Growth, MMP Secretion and Invasion by a Nutrient Mixture on Head and Neck Squamous Carcinoma Cell Line FaDu: In Vitro and In Vivo Studies
(Scientific Presentations: Cancer)
... (NM) containing ascorbic acid, lysine, proline, and green tea extract on human HNSCC cell line FaDu in vitro, evaluating viability, MMP secretion, invasion and morphology. In vivo studies were carried ...
Created on 03 April 2015
40. A Novel Nutrient Mixture Inhibits Cell Proliferation, MMP Secretion and Invasion in HepG2 Hepatoma Cell Line
(Scientific Presentations: Cancer)
... we examined NM for its effect on proliferation, MMP secretion, invasion, morphology, and apoptosis. Methods:  HepG2 cells (ATCC) were cultured in MEM medium supplemented with 10% FBS and antibiotics. ...
Created on 03 April 2015