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61. A Nutrient Mixture Induces Caspase Dependent Apoptosis in Human Synovial Sarcoma Cells
(Sarcomas)
M.W. Roomi, B Bhanap, Ahmed T, A Niedzwiecki, M Rath Department of Oncology, Dr. Rath Research Institute, USA J Sarcoma Res. 2018; 2(1): 1010 -1014 Abstract:  Synovial sarcoma is a rare soft ...
Created on 28 January 2019
62. Effects of Various Multi-Nutrient Supplements on the Production and Extracellular Deposition of Collagen I and IV by Human Aortic Smooth Muscle Cells
(Heart Disease)
... and Natural Health (August 2018) Abstract: Chronic vitamin deficiency is an underlying cause of many modern human chronic diseases, including cardiovascular disease (CVD).1 A major pathological mechanism ...
Created on 28 January 2019
63. A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells
(Female Reproductive Cancer)
M. Waheed Roomi, Bilwa Bhanap, Aleksandra Niedzwiecki*, Matthias Rath Dr. Rath Research Institute, Oncology Department, Santa Clara, California, USA Journal of Cervical Cancer Research, 2018, 2(1), ...
Created on 28 January 2019
64. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
(Other Aspects of Cancer)
... develop an anti-cancer vaccine by inhibiting these specific enzymes. We selected three oligopeptides from human MMP-9 and one from human MMP-2. We demonstrated the efficacy of these oligopeptides in generating ...
Created on 23 January 2019
65. Induction of Apoptosis in Human Lung Cancer Cells (A-549) by a Novel Nutrient Mixture via Upregulation of Caspase Enzymes
(Other Aspects of Cancer)
M.W. Roomi, Ph.D., Ahmed T, A. Niedzwiecki, Ph.D., M. Rath, M.D. Dr. Rath Research Institute,  1260 Memorex Drive, Santa Clara, CA 95050 Austin J Lung Cancer Res. 2018; 3(1): 1013 – 1016 Abstract:  ...
Created on 23 January 2019
66. Modulation of MMP-2 and -9 Secretion by Cytokines, Inducers and Inhibitors in Human Melanoma A-2058 Cells
(Skin Cancer)
... inducers and inhibitors control MMP activities. We investigated the roles of these in regulation of MMP-2 and -9 in human melanoma A-2058 cells. Human A-2058 cells were grown in DMEM supplemented with ...
Created on 26 April 2017
67. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
(Head & Neck Cancers)
... to spread to distal organs. Various cytokines, mitogens, growth factors, inducers and inhibitors control MMP activity. We investigated the roles of these in the regulation of MMP-2 and MMP-9 in human glioblastoma ...
Created on 28 March 2017
68. Cytokines, Inducers And Inhibitors Modulate Mmp-2 And Mmp‑9 Secretion By Human Fanconi Anemia Immortalized Fibroblasts
(Head & Neck Cancers)
... regulation of MMP-2 and MMP-9 in human immortalized fibroblasts from FA. Human FA immortalized fibroblast cell lines FA-A:PD220 and FA-D2:PD20 were grown in minimum essential medium (MEM) supplemented ...
Created on 28 March 2017
69. Effects of Ascorbic Acid on Tax, NF-κB and MMP-9 in Human T-cell Lymphotropic Virus Type 1 Positive Malignant T-Lymphocytes
(Blood Cancer)
... independent of this mechanism and follow a different approach. Key words: Acute T-cell leukemia, Human T-cell Lymphotrophic Virus type I (HTLV-1), Tax, NF-κB pathway, Matrix metalloproteinase-9 (MMP-9), ...
Created on 05 January 2017
70. Apoptosis of Human Fibrosarcoma Cells HT-1080 Triggered by a Novel Nutrient Mixture via Induction of Caspases
(Sarcomas)
... in athymic mice. Based on the observation, we investigated whether this phenomenon and the anti-cancer effects were due to the induction of apoptosis. Human fibrosarcoma cells HT-1080 were cultured in ...
Created on 09 March 2016
71. Effect Of A Novel Nutrient Mixture On Fanconi Anemia Fibroblast And Normal Human Dermal Fibroblast: A Comparison
(Scientific Presentations: Cancer)
... characterized by progressive bone marrow failure, congenital defect and cancer predisposition. Cell culture from FA fibroblast (FAF) displays certain abnormalities as compared to normal human dermal fibroblast ...
Created on 17 September 2015
72. In Vivo and In Vitro Antitumor Effect of Ascorbic Acid, Lysine, Proline, Arginine and Green Tea Extract on Human Fibrosarcoma Cells HT-1080
(Sarcomas)
... in vitro on human fibrosarcoma cells HT-1080 by measuring: cell proliferation, modulation of MMP-2 and MMP-9, and invasive potential.   Methods: In vivo, we studied the growth of human fibrosarcoma ...
Created on 20 April 2015
73. Modulation Of Upa, Mmps And Their Inhibitors By A Novel Nutrient Mixture In Human Colorectal, Pancreatic And Hepatic Carcinoma Cell Lines
(Gastrointestinal Cancers)
Roomi MW, Kalinovsky T, Niedzwiecki A, Rath M Dr. Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050 International Journal of Oncology –2015; 47(1): 370-376 Abstract: Colorectal, ...
Created on 15 April 2015
74. Anticancer Effect of Lysine, Proline, Arginine, Ascorbic Acid and Green Tea Extract on Human Renal Adenocarcinoma Line 786-0
(Kidney and Bladder Cancer)
... acid, and green tea extract on human renal adenocarcinoma cell line 786-0 by measuring: cell proliferation, modulation of MMP-2 and –9 secretion, and cancer cell invasive potential. Methods: Human ...
Created on 14 April 2015
75. Modulation of Human Renal Cell Carcinoma 786-0 MMP-2 and MMP-9 Activity by Inhibitors and Inducers in Vitro
(Kidney and Bladder Cancer)
... We therefore investigated the effect of inducers and inhibitors on RCC 786-0 in vitro. Methods: Human RCC 786-0 ATCC) was grown in RPMI medium supplemented with 10% FBS, penicillin, and streptomycin ...
Created on 14 April 2015
76. Effect of a nutrient mixture on the localization of extracellular matrix proteins in HeLa human cervical cancer xenografts in female nude mice
(Female Reproductive Cancer)
M.W. Roomi, T. Kalinovsky,  A. Niedzwiecki and M. Rath Dr. Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050 International Journal of Oncology 2015 DOI: 10.3892/ijo.2015.3008 Abstract: ...
Created on 09 April 2015
77. Cytotoxic Effect of Lipophilic Substitution at 2-, 6-, and 2,6-Positions in Ascorbic Acid and Expression of Matrix Metalloproteinases in Hep G2 Cells, Melanoma Cells, and Normal Human Dermal Fibroblas ...
(Scientific Presentations: Cancer)
Roomi MW, Netke SP, Ivanov V, Niedzwiecki A, Rath M. Presented at:  American College of Nutrition, 42nd Annual Meeting, Orlando, Florida, Oct. 3-7, 2001. Published in:  Journal of the American College ...
Created on 04 April 2015
78. Inhibitory Effects of Ascorbic Acid, Proline, and Lysine Supplementation on Matrigel Invasion by Human Breast Cancer Cells MDA-MB-231
(Scientific Presentations: Cancer)
Netke SP, Ivanov V, Roomi MW, Niedzwiecki A, Rath M. Presented at:  19th Annual Miami Breast Cancer Conference, Miami Beach, Florida, February 27–March 3, 2002. Published in:  Conference Proceedings. ...
Created on 04 April 2015
79. Metastatic and Cytoxic Effects of Ascobigen and Iso-Ascorbigen in Human Cancer Cell Lines
(Scientific Presentations: Cancer)
M.W. Roomi, A. Bogale, V. Ivanov, S. Netke, A. Niedzwiecki and M. Rath Presented at:  American College of Nutrition, 43rd Annual Meeting, San Antonio, Texas, Oct. 3-6, 2002. Published in:  J. Am. Coll. ...
Created on 04 April 2015
80. Matrix Metalloproteinase-2 Inhibition and Invasion Potential in Human Chondrocytes by Nutrient Synergy – A Specific Mixture of Nutrients Containing Lysine, Proline, Ascorbic Acid and Epigallocatechin  ...
(Scientific Presentations: Cancer)
Roomi MW, Ivanov V, Netke SP, Niedzwiecki A, Rath M Presented at:  American Association of Cancer Research Special Conference in Cancer Research: Proteases, Extracellular Matrix and Cancer, Hilton Head ...
Created on 04 April 2015