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61. Progress of Tumor Growth and Metastasis After Inoculation of B16FO Melanoma Cells in Kidney of Female Nude Mice Is Inhibited by a Novel Nutrient Mixture
(Skin Cancer)
... B16FO melanoma cells into the left kidney of female nude mice. Female athymic mice (n = 10) 8 to 10 weeks of age, were inoculated superficially in the left kidney with 5 × 105 B16FO melanoma cells in 100 ...
Created on 08 May 2019
62. A Novel Nutrient Mixture Induces Apoptosis in Human Mesothelioma Cells (MSTO-211H) via Activation of Caspases
(Lung Cancer)
... nutrient mixture was seen to block MMP secretion and invasion through MatrigelTM by mesothelioma cells. In the current study, we wanted to explore if the nutrient mixture could induce apoptosis in mesothelioma ...
Created on 08 May 2019
63. A Nutrient Mixture Induces Caspase Dependent Apoptosis in Human Synovial Sarcoma Cells
(Sarcomas)
... and the cells were treated with NM at 0-1000 μg/ml concentration. Cell cytotoxicity was measured by MTT assay, morphology by H&E staining, and the apoptosis by Green Caspases. NM showed no significant ...
Created on 28 January 2019
64. Effects of Various Multi-Nutrient Supplements on the Production and Extracellular Deposition of Collagen I and IV by Human Aortic Smooth Muscle Cells
(Heart Disease)
... leading to the development of CVD is loss of vascular-wall integrity, a structural weakness that triggers the atherosclerotic process.2 The arterial wall is composed of the constituent cells and surrounding ...
Created on 28 January 2019
65. A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells
(Female Reproductive Cancer)
...  Based on those results, we studied weather, the antitumor effects  are  due  to  induction  of  apoptosis  in  these  cancers.  Cervical  cancer  cell  like  (HeLa)  and  ovarian  cancer  cells  line  ...
Created on 28 January 2019
66. Induction of Apoptosis in Human Lung Cancer Cells (A-549) by a Novel Nutrient Mixture via Upregulation of Caspase Enzymes
(Other Aspects of Cancer)
... cells. Furthermore, our studies also showed that prior supplementation of nutrient mixture was able to reduce urathane induced lung cancer in male A/J mice. Based on the observation, we questioned ...
Created on 23 January 2019
67. Down regulation of u-Pa by a nutrient mixture In hemangioma (eoma) cells by inducing Caspase-dependent apoptosis
(Other Aspects of Cancer)
... cell lines was used as an experimental composition. EOMA cells were grown in appropriate media with antibiotics in 24- well tissue culture plates. At near confluence, the cells were treated with nutrition ...
Created on 19 June 2018
68. Anti-cancer potential of a specific mixture of phytonutrients in bone cancer cells
(Sarcomas)
... curcumin, resveratrol and green tea extract on several parameters associated with the development of this type of cancer. The chondrosarcoma cells SW-1353 exposed to PB concentrations of 10, 25, 50, ...
Created on 06 February 2018
69. Modulation of MMP-2 and -9 Secretion by Cytokines, Inducers and Inhibitors in Human Melanoma A-2058 Cells
(Skin Cancer)
... metalloproteinase (MMP)-2 and -9 secretions that degrade the extracellular matrix and basement membrane, allowing cancer cells to spread to distal organs.   Various cytokines, mitogens, growth factors, ...
Created on 26 April 2017
70. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
(Head & Neck Cancers)
... tumors are highly aggressive, characterized by the secretion of high levels of matrix metalloproteinase (MMP)-2 and MMP-9 that degrade the extracellular matrix and basement membrane, allowing cancer cells ...
Created on 28 March 2017
71. In Vitro Modulation of MMP-2 and MMP-9 Secretion by Cytokines, Inducers, and Inhibitors in Head and Neck Squamous Carcinoma Cells (FaDu) and Tongue Carcinoma Cells (SCC-25)
(Head & Neck Cancers)
... compared MMP secretion by various cytokines, inducers, mitogen, inhibitors that regulate MMP-2 and MMP-9 activities in FaDu and Tongue cancer cell lines. The cells were grown in appropriate media, at near ...
Created on 06 February 2017
72. Antiproliferative Effects of Antioxidants Using HTLV-1 Positive and Negative Malignant T-Cells
(Scientific Presentations: Infectious Diseases)
... the growth of virus-infected and virus-negative leukemia cell types. These nutrients were used in concentrations that did not affect the viability of normal cells, but were effective in killing leukemia ...
Created on 17 April 2016
73. Apoptosis of Human Fibrosarcoma Cells HT-1080 Triggered by a Novel Nutrient Mixture via Induction of Caspases
(Sarcomas)
... in athymic mice. Based on the observation, we investigated whether this phenomenon and the anti-cancer effects were due to the induction of apoptosis. Human fibrosarcoma cells HT-1080 were cultured in ...
Created on 09 March 2016
74. In Vivo and In Vitro Antitumor Effect of Ascorbic Acid, Lysine, Proline, Arginine and Green Tea Extract on Human Fibrosarcoma Cells HT-1080
(Sarcomas)
... in vitro on human fibrosarcoma cells HT-1080 by measuring: cell proliferation, modulation of MMP-2 and MMP-9, and invasive potential.   Methods: In vivo, we studied the growth of human fibrosarcoma ...
Created on 20 April 2015
75. Cytotoxic Effect of Lipophilic Substitution at 2-, 6-, and 2,6-Positions in Ascorbic Acid and Expression of Matrix Metalloproteinases in Hep G2 Cells, Melanoma Cells, and Normal Human Dermal Fibroblas ...
(Scientific Presentations: Cancer)
Roomi MW, Netke SP, Ivanov V, Niedzwiecki A, Rath M. Presented at:  American College of Nutrition, 42nd Annual Meeting, Orlando, Florida, Oct. 3-7, 2001. Published in:  Journal of the American College ...
Created on 04 April 2015
76. Inhibitory Effects of Ascorbic Acid, Proline, and Lysine Supplementation on Matrigel Invasion by Human Breast Cancer Cells MDA-MB-231
(Scientific Presentations: Cancer)
...   Comment The results from this study demonstrated that while an individual nutrient, such as ascorbic acid, can inhibit the invasion of cancer cells through Matrigel (a model for extracellular matrix), ...
Created on 04 April 2015
77. Inhibitory Effect of Nutrient Synergy, a Specific Formulation of Nutrients Containing Lysine, Proline, Ascorbic Acid, and Epigallocatechin Gallate, on Matrix Metalloproteinase Activity and Invasion of ...
(Scientific Presentations: Cancer)
... FASEB Journal, 17 (Part II, #5) p. A1368, Abstract #867:1, March 2003.   Comment To reproduce and spread to other parts in the body, cancer cells degrade the extracellular matrix (ECM) by secreting ...
Created on 04 April 2015
78. Nutrient Synergy Counteracts Carcinogenic Activity of Estrogen in Cultured Human Cancer Cells
(Scientific Presentations: Cancer)
Ivanov V, Roomi MW, Niedzwiecki A, Rath M Presented at:  American College of Nutrition, Nashville, Tennessee, October 9-12, 2003. Published in:  Journal of the American College of Nutrition, 22 (5):466, ...
Created on 04 April 2015
79. Anti-Proliferative Effects of Antioxidants Using HTLV-1 Positive and Negative Malignant T-Cells
(Scientific Presentations: Cancer)
... were effective in inhibiting the growth of virus-infected and virus-negative leukemia cell types. These nutrients were used in concentrations that did not affect the viability of normal cells, but were ...
Created on 03 April 2015
80. Naturally Produced Extracellular Matrix Inhibits Growth Rate and Invasiveness of Human Osteosarcoma Cancer Cells
(Scientific Presentations: Cancer)
V. Ivanov, V. Ivanova, M.W. Roomi, A. Niedzwiecki and M. Rath Matthias Rath BV, Santa Clara, CA 95050 Presented at:  American College of Nutrition Symposium on Advances on Clinical Nutrition, Long Beach, ...
Created on 03 April 2015