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81. Synergistic Anti-Borreliae Efficacy of a Composition of Naturally-occurring Compounds: an In vitro Study
(Lyme Disease)
... and persistent forms of Borrelia spp. Methods: A formulation of six plant-derived compounds combined at their 1/32-1/2 MIC values was tested in vitro against two species of Borrelia recognized as causative ...
Created on 07 December 2019
82. 10-undecynoic acid is a new anti-adherent agent killing biofilm of oral Streptococcus spp.
(Infectious Disease)
A. Goc, W. Sumera, A. Niedzwiecki, M. Rath PLOS ONE | https://doi.org/10.1371/journal.pone.0214763 April, 2019 Abstract: In the search for novel agents against oral pathogens in their planktonic and ...
Created on 07 December 2019
83. Sathvika Gopalasetty
(Future Scientist)
... cause cells to become immortalized and grow out of control. These abnormal cancer cells rapidly multiply and spread, crowding out normal cells and disrupting their function. Cancer is the second leading ...
Created on 20 September 2019
84. Future Scientists
(Future Scientist)
... their scientific and medical careers. They can shape up the future of our individual and global health by practicing and promoting Cellular Medicine and prioritizing health solutions that are safe and ...
Created on 11 September 2019
85. Vitamin C in Health: Scientific focus on its anti-cancer efficacy
(Other Aspects of Cancer)
... effect in cancer treatment. There are a wide variety of mechanisms by which vitamin C kills cancer cells and prevents their spread which include its roles as an anti-oxidant, an inhibitor of metalloproteinases ...
Created on 23 August 2019
86. Health-related assessment of a vitamin and mineral supplement in school age children
(Others)
... complex with school meals (n = 69, the vitamin group) while children in the control group (n = 34) received only their regular school meals. Evaluation of the children was carried out before and after ...
Created on 23 August 2019
87. Comparison of the antioxidant efficacy and cellular protection by several categories of nutritional supplements on the market
(Others)
... in many diseases. Many people use nutritional supplements to maintain and improve their health. However, there is little information on how, or even if, popular dietary supplements improve cellular health ...
Created on 23 August 2019
88. Anti-cancer potential of a specific mixture of phytonutrients in bone cancer cells
(Bone Cancer)
... 10, 25, 50, and 100 µg/ml were tested for cell proliferation/viability, morphology, matrix metalloproteinase (MMP) secretion, as well as their invasive and migration abilities. Cell proliferation was carried ...
Created on 23 August 2019
89. Effects of Various Multi-Nutrient Supplements on the Production and Extracellular Deposition of Collagen I and IV by Human Aortic Smooth Muscle Cells
(Heart Disease)
... Since there are no regulatory requirements demanding scientific proof of the efficacy of nutritional supplements marketed to consumers, many manufacturers promote their products using mere marketing slogans. ...
Created on 28 January 2019
90. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
(Other Aspects of Cancer)
...  If confirmed by further in vivo and later clinical studies, a vaccine for the prevention and treatment of all types of cancers – irrespective of their origin and type – may become available. Moreover, ...
Created on 23 January 2019
91. Anti-cancer potential of a specific mixture of phytonutrients in bone cancer cells
(Sarcomas)
... and 100 µg/ml were tested for cell proliferation/viability, morphology, matrix metalloproteinase (MMP) secretion, as well as their invasive and migration abilities. Cell proliferation was carried out by ...
Created on 06 February 2018
92. Reciprocal cooperation of phytochemicals and micronutrients against typical and atypical forms of Borrelia spp.
(Lyme Disease)
... public health threat. Current treatments based on antibiotics often lead to relapse after their withdrawal. Naturally derived substances that could work synergistically to display higher efficacy compared ...
Created on 23 June 2017
93. Composition of plant-derived compounds as an alternative approach for Lyme patients. A Lesson from the pre-clinical study.
(Scientific Presentations: Infectious Diseases)
... of LD, which calls for the development of new treatments. Naturally derived substances that are safe and if properly combined, could have enhanced efficacy through their synergistic or additive interactions, ...
Created on 20 June 2017
94. Nutrient Synergy: A Novel Approach To Head And Neck Cancer (Chapter 1)
(Head & Neck Cancers)
... poor prognosis. Matrix metalloproteinases (MMPs), especially MMP-2 and -9, play critical roles in degradation of the extracellular matrix and their expression in head and neck carcinoma have been associated ...
Created on 28 March 2017
95. In Vitro Modulation of MMP-2 and MMP-9 Secretion by Cytokines, Inducers, and Inhibitors in Head and Neck Squamous Carcinoma Cells (FaDu) and Tongue Carcinoma Cells (SCC-25)
(Head & Neck Cancers)
... Matrix metalloproteinases (MMPs), specifically, MMP-2 and MML-9 play a critical role in tumorigenesis by their ability to modify tumor microenvironments, facilitating cell invasion and metastasis. We ...
Created on 06 February 2017
96. Cooperation of Doxycycline with Phytochemicals and Micronutrients Against Active and Persistent Forms of Borrelia sp
(Lyme Disease)
... and micronutrients represent a growing theme in antimicrobial defense; however, little is known about their anti-borreliae effects of reciprocal cooperation with antibiotics. A better understanding of ...
Created on 19 September 2016
97. The anti-borreliae efficacy of phytochemicals and micronutrients: an update
(Lyme Disease)
... little is known about their effects against Borrelia burgdorferi sensu lato, the causative pathogens of Lyme disease. A better understanding of this aspect could advance knowledge about pathophysiology ...
Created on 19 September 2016
98. Lipoprotein(A) And Vitamin C Impair Development Of Breast Cancer Tumors In Lp(A)+; Gulo-/- Mice
(Breast Cancer)
... positively for Lp(a) and their size was inversely proportional to Lp(a) serum levels. The results implicate that Lp(a) may play a role in controlling tumor growth and expansion. The most likely mechanism ...
Created on 04 July 2016
99. Reciprocal Cooperation of Phytochemicals against Borrelia burgdorferi and Borrelia garinii
(Scientific Presentations: Infectious Diseases)
... defense, however, little is known about their anti-borrelaea reciprocal cooperation. To better understand this subject, we studied the efficacy of selected phytochemicals such as flavones and fatty acids ...
Created on 20 June 2016
100. Evaluation of Vitamin D3 and Vitamin C in Cooperation with Doxycycline against Borrelia burgdorferii and Borrlia garinii
(Scientific Presentations: Infectious Diseases)
... such cooperation, we studied the anti-bacterial efficacy of vitamin D3 and vitamin C (known for their antimicrobial activity) with doxycycline (one of the most frequently prescribed drugs for Lyme patients) ...
Created on 16 June 2016