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81. A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells
(Female Reproductive Cancer)
... (SK-OV-3)  were  cultured  in  DME  media  and  cells  were  treated  with  the  nutrient  mixture  at  0-1000  μg/ml  doses.  Cell proliferation  was  measured  by  MTT  assay,  morphology  was  studied  ...
Created on 28 January 2019
82. Induction of Apoptosis in Human Lung Cancer Cells (A-549) by a Novel Nutrient Mixture via Upregulation of Caspase Enzymes
(Other Aspects of Cancer)
... whether cell apoptosis was partially responsible for this phenomenon. The lung cancer cells A-549 were cultured in complete Ham F-12K medium and the cells were treated with NM at 0-1000 μg/ml concentration. ...
Created on 23 January 2019
83. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
(Other Aspects of Cancer)
... immune response in mice. The  in vitro tests showed that anti-MMPs sera were effective in curbing invasion of HeLA cells through the extracellular matrix system (Matrigel). In our in vivo studies, ...
Created on 23 January 2019
84. Down regulation of u-Pa by a nutrient mixture In hemangioma (eoma) cells by inducing Caspase-dependent apoptosis
(Other Aspects of Cancer)
... cell lines was used as an experimental composition. EOMA cells were grown in appropriate media with antibiotics in 24- well tissue culture plates. At near confluence, the cells were treated with nutrition ...
Created on 19 June 2018
85. Anti-cancer potential of a specific mixture of phytonutrients in bone cancer cells
(Sarcomas)
... and 100 µg/ml were tested for cell proliferation/viability, morphology, matrix metalloproteinase (MMP) secretion, as well as their invasive and migration abilities. Cell proliferation was carried out by ...
Created on 06 February 2018
86. Programmed Cell Death in Renal Cancer Cell 786-0 by a Novel Nutrient Mixture by Down Regulating u-PA, MMPs, and Up Regulating TIMPs
(Kidney and Bladder Cancer)
... proline exhibited anticancer effects in various cancers. In this study, we investigated whether the anti-cancer properties of NM were due to the induction of apoptosis. The RCC cells (786-0) were cultured ...
Created on 05 February 2018
87. Inhibition of proliferation and induction of apoptosis by a novel phytobiological mixture against breast cancer cell lines
(Scientific Presentations: Cancer)
... and curcumin at different proportions. Theanti-proliferative and pro-apoptotic effects of PB were evaluated at non-cytotoxic concentrations as determined usingthe Sulfa-Rhodamine B assay (SRB).The effects ...
Created on 06 December 2017
88. Composition of Plant-derived Compounds as an Alternative Approach to Lyme disease
(Scientific Presentations: Infectious Diseases)
... or additively to display higher efficacy compared to the individual components may serve as such an alternative for Lyme patients. Over 50 non-synthetic plant-derived active compounds and extracts were ...
Created on 20 June 2017
89. Composition of plant-derived compounds as an alternative approach for Lyme patients. A Lesson from the pre-clinical study.
(Scientific Presentations: Infectious Diseases)
... in their symptoms were included in the study. Findings: After 6 months, 3/17 of the patients were completely symptom-free and had a very good energy status both physically and psychologically and able ...
Created on 20 June 2017
90. Modulation of MMP-2 and -9 Secretion by Cytokines, Inducers and Inhibitors in Human Melanoma A-2058 Cells
(Skin Cancer)
... inducers and inhibitors control MMP activities. We investigated the roles of these in regulation of MMP-2 and -9 in human melanoma A-2058 cells. Human A-2058 cells were grown in DMEM supplemented with ...
Created on 26 April 2017
91. Nutrient Synergy: A Novel Approach To Head And Neck Cancer (Chapter 1)
(Head & Neck Cancers)
... OHSU-974 cells lines. In addition, secretion of MMPs, invasion through Matrigel and migrations of head and neck cancer cells were down regulated by the nutrient mixtures studied. Furthermore, the nutrient ...
Created on 28 March 2017
92. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
(Head & Neck Cancers)
... T-98G cells. Human T-98G cells were grown in DME supplemented with 15% fetal bovine serum and antibiotics in 24-well tissue culture plates. At near confluence, cells were washed with phosphate-buffered ...
Created on 28 March 2017
93. Cytokines, Inducers And Inhibitors Modulate Mmp-2 And Mmp‑9 Secretion By Human Fanconi Anemia Immortalized Fibroblasts
(Head & Neck Cancers)
... regulation of MMP-2 and MMP-9 in human immortalized fibroblasts from FA. Human FA immortalized fibroblast cell lines FA-A:PD220 and FA-D2:PD20 were grown in minimum essential medium (MEM) supplemented ...
Created on 28 March 2017
94. A Specific Mixture Of Nutrients Suppresses Ovarian Cancer A-2780 Tumor Incidence, Growth, And Metastasis To Lungs
(Female Reproductive Cancer)
... lysine, proline, green tea extract, and quercetin on human ovarian cancer cell A-2780 in vivo and in vitro. Athymic female nude mice (n = 12) were all inoculated intraperitoneally (IP) with 2 x106 ...
Created on 20 March 2017
95. In Vitro Modulation of MMP-2 and MMP-9 Secretion by Cytokines, Inducers, and Inhibitors in Head and Neck Squamous Carcinoma Cells (FaDu) and Tongue Carcinoma Cells (SCC-25)
(Head & Neck Cancers)
... compared MMP secretion by various cytokines, inducers, mitogen, inhibitors that regulate MMP-2 and MMP-9 activities in FaDu and Tongue cancer cell lines. The cells were grown in appropriate media, at near ...
Created on 06 February 2017
96. Effects of Ascorbic Acid on Tax, NF-κB and MMP-9 in Human T-cell Lymphotropic Virus Type 1 Positive Malignant T-Lymphocytes
(Blood Cancer)
... effect of AA were studied by LDH release and MTT tests, respectively. The proteins expression level was assessed by western blotting. RT-PCR was used to study mRNAs level. Finally, ELISA/EMSA and Zymography ...
Created on 05 January 2017
97. Cooperation of Doxycycline with Phytochemicals and Micronutrients Against Active and Persistent Forms of Borrelia sp
(Lyme Disease)
... iodine, rosmarinic acid, and monolaurin, as well as, vitamins D3 and C were tested in a combinations with doxycycline for their in vitro effectiveness against vegetative (spirochetes) and latent (rounded ...
Created on 19 September 2016
98. Lipoprotein(A) And Vitamin C Impair Development Of Breast Cancer Tumors In Lp(A)+; Gulo-/- Mice
(Breast Cancer)
... C synthesis and the production of human Lp(a).  Female Lp(a)+;Gulo(-/-) and control wild type Balb/c mice without these two metabolic features were orthotopically inoculated with 4T1 breast cancer cells ...
Created on 04 July 2016
99. Reciprocal Cooperation of Phytochemicals against Borrelia burgdorferi and Borrelia garinii
(Scientific Presentations: Infectious Diseases)
... to ascertain the type of their related cooperation against Borrelia sp. Methods: Phytochemicals such as baicalein, luteolin, 10-HAD, and glycerol monolaurate were tested in different “two-agent” combinations ...
Created on 20 June 2016
100. Evaluation of Vitamin D3 and Vitamin C in Cooperation with Doxycycline against Borrelia burgdorferii and Borrlia garinii
(Scientific Presentations: Infectious Diseases)
... analysis was performed for further validation. All experiments were performed in triplicates. Results: The results showed that doxycycline in combination with vitamin D3 exhibits synergistic anti-spirochetal ...
Created on 16 June 2016