- 61. Simultaneous Inhibition of SARS-CoV-2 Infectivity by a Specific Combination of Plant-derived Compounds
- (Coronavirus)
- ... pandemic remains a challenge to human health and economy worldwide. Previously we have shown that a combination of active plant-derived compounds and plant extracts can dose-dependently inhibit binding ...
- Created on 23 September 2021
- 62. Dietary Vitamin C and Age-Induced Lipid and Hormonal Metabolic Changes in a Humanized Mouse Model Not Synthesizing Vitamin C and Producing Lipoprotein(a) [Gulo (−/−); Lp(a)+]
- (Aging)
- ... suitable for the study of metabolic aspects relevant to human metabolism. It is a well-known fact that vitamin C is essential in collagen synthesis, and in maintaining extracellular matrix integrity, as ...
- Created on 23 June 2021
- 63. Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions
- (Coronavirus)
- ... to the host receptor in order to prevent its entry has been of particular interest. Here, we provide experimental evidence that, among 56 tested polyphenols, including plant extracts, brazilin, theaflavin-3,3’-digallate, ...
- Created on 22 June 2021
- 64. Micronutrients in mitigating the adverse health effects of air pollution – part 2
- (Others)
- ... disease (COPD), lung cancer, and acute lower respiratory infections in children. Yet, 92% of the world population lives in places that exceed the WHO air quality guidelines. On the other hand, laboratory ...
- Created on 11 June 2021
- 65. Simultaneous inhibition of key mechanisms of SARS-CoV-2 infectivity by a specific combination of polyphenols
- (Scientific Presentations: Infectious Diseases)
- ... pandemic remains a challenge to human health and economy worldwide. Previously we have shown that a combination of active plant-derived compounds and plant extracts can dose-dependently inhibit binding ...
- Created on 14 May 2021
- 66. Anti-borreliae efficacy of Gallic acid in vitro
- (Scientific Presentations: Infectious Diseases)
- ... still sought after due to the growing number of newly infected patients or those that relapse after discontinuation of antibiotic application. In this study, we investigated whether a trihydroxybenzoic ...
- Created on 12 May 2021
- 67. Polyunsaturated ω‑3 fatty acids inhibit ACE2‑controlled SARS‑CoV‑2 binding and cellular entry
- (Coronavirus)
- ... sequence, we observed that polyunsaturated fatty acids most efectively interfere with binding to hACE2, the receptor for SARSCoV-2. Using a spike protein pseudo-virus, we also found that linolenic acid ...
- Created on 05 May 2021
- 68. Inhibition of ACE2 expression by Ascorbic acid alone and its combination with other natural compounds
- (Coronavirus)
- ... compounds can affect ACE2 expression. Results: The results show that ascorbic acid itself has moderate but consistent lowering effects on ACE2 expression at the cellular, protein, and RNA levels. Some ...
- Created on 17 February 2021
- 69. Scientific basis of micronutrient applications as an effective, safe, and affordable global public health strategy to help control the coronavirus pandemic
- (Coronavirus)
- ... and energy, among many other aspects. 2 This statement highlights the important, but often overlooked, fact that healthy nutrition supplying a full spectrum of micronutrients is the foundation of our immune ...
- Created on 02 February 2021
- 70. The micronutrient combination with immune-enhancing effects
- (Coronavirus)
- ... for novel non-toxic and effective approaches with immune system- enhancing effects, so it can resist and fight these infections is still sought after. It has been firmly established that both nutrition ...
- Created on 08 October 2020
- 71. Fat Soluble vitamins affect composition of extracellular matrix deposited by human aortic smooth muscle and endothelial cells in vitro
- (Heart Disease)
- ... process that is associated with coronary atherosclerosis, and is a prognostic marker of cardiovascular morbidity and mortality. The process of arterial wall calcification is triggered and accompanied by ...
- Created on 28 August 2020
- 72. Micronutrient combination inhibits two key steps of coronavirus (SARS-CoV-2) infection: viral binding to ACE2 receptor and its cellular expression
- (Coronavirus)
- ... to human health as well as global economies. The quest for vaccines and other approaches to this pandemic thus far focuses on synthetic molecules that are – predictably – associated with a variable degree ...
- Created on 27 August 2020
- 73. Immunological targeting of matrix metalloproteinase-9 as a novel approach to universal cancer vaccine: Characterization of anticancer antibodies efficacy in vitro
- (MMP)
- ... door for effective prevention and even cure. We previously reported that mice immunized with synthetic oligopeptides containing specific amino acid sequences from human MMP-2 and MMP-9 showed a significant ...
- Created on 11 August 2020
- 74. Effective and safe global public health strategy to fight the COVID-19 pandemic: Specific micronutrient combination inhibits Coronavirus cell-entry receptor (ACE2) expression
- (Publications)
- ... a fact documented in every leading textbook of biology. This study provides scientific evidence that, in addition, specific micronutrient compositions are powerful tools in the fight against the COVID-19 ...
- Created on 02 July 2020
- 75. Scientific Breakthough Towards Natural Control of the Pandemic
- (Publications)
- ... in every leading textbook of biology. This study provides scientific evidence that, in addition, specific micronutrient combination are powerful tools in the fight against the COVID-19 pandemic. Both, ...
- Created on 29 June 2020
- 76. Effective and safe global public health strategy to fight the COVID-19 pandemic: Specific micronutrient composition inhibits Coronavirus cell-entry receptor (ACE2) expression
- (Coronavirus)
- ... general immune resistance against infections, a fact documented in every leading textbook of biology. This study provides scientific evidence that, in addition, specific micronutrient compositions are ...
- Created on 29 June 2020
- 77. Specific composition of polyphenolic compounds with fatty acids as an approach in helping to reduce spirochete burden in Lyme disease: in vivo and human observational study
- (Lyme Disease)
- ... Methods: To determine a suitable approach that would help reduce this number, we examined the efficacy of a composition of polyphenolic compounds (baicalein, luteolin, and rosmarinic acid) with fatty ...
- Created on 13 June 2020
- 78. Expanding Metabolic Targets in Cancer by Select Combinations of Vitamin C and EGCG with Different Natural Compounds
- (Other Aspects of Cancer)
- ... can overcome the metabolic limitations of individual components and enhance the scope of their therapeutic efficacy. In this aspect, our in vitro and in vivo studies have shown that synergy-based interaction ...
- Created on 08 February 2020
- 79. Matrix metalloproteinases-9 as a promising target for anti-cancer vaccine: inhibition of melanoma tumor growth in mice immunized with syngeneic MMP-9 peptides
- (MMP)
- ... could open the door for effective prevention and even cure. We previously reported that mice immunized with synthetic oligopeptides containing specific amino acid sequences from human MMP-2 and MMP-9 showed ...
- Created on 08 February 2020
- 80. Progress of Tumor Growth and Metastasis after Inoculation of B16FO Melanoma Cells in Kidney of Female Nude Mice Is Inhibited by a Novel Nutrient Mixture
- (Skin Cancer)
- ... deaths. Melanoma is a serious cancer that metastasizes to other areas of the body, including the lungs, liver, brain, bones, or lymph nodes. Currently used cancer therapies are ineffective with a high ...
- Created on 08 February 2020