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61. Expanding Metabolic Targets in Cancer by Select Combinations of Vitamin C and EGCG with Different Natural Compounds
(Other Aspects of Cancer)
... such as surgery, chemotherapy, and radiation are associated with multiple side effects. Nutraceuticals including vitamins, minerals, amino acids, and several phytochemicals derived from diet are known ...
Created on 08 February 2020
62. Matrix metalloproteinases-9 as a promising target for anti-cancer vaccine: inhibition of melanoma tumor growth in mice immunized with syngeneic MMP-9 peptides
(MMP)
... types of cancer – invasion and metastasis. The elevated levels of ma-trix metalloproteinases, such as MMP-9 play a key role in tumorigenesis, angiogenesis, apoptosis, cancer invasion and metastasis. Among ...
Created on 08 February 2020
63. Synergistic Anti-Borreliae Efficacy of a Composition of Naturally-occurring Compounds: an In vitro Study
(Lyme Disease)
... its inhibitory effect on the release of IL-1α, IL-1β, and IL-6 by human CD14+ monocytes stimulated with live Borrelia sp. Conclusion:: These results suggest that such a formulation of compounds might ...
Created on 07 December 2019
64. Sathvika Gopalasetty
(Future Scientist)
... cells in the body. These are the cells which line the surfaces of the organs. Cancer that originates in epithelial surfaces, such as the gastrointestinal tract, respiratory tract, biliary tract, and skin, ...
Created on 20 September 2019
65. Vitamin C in Health: Scientific focus on its anti-cancer efficacy
(Other Aspects of Cancer)
... combination with other micronutrients such as lysine, arginine, proline and green tea extract. The synergistic effect of these nutrient mixtures can thus be considered in preventive and therapeutic aspects ...
Created on 23 August 2019
66. Cell damaging effects of glyphosate – Are we ready for Roundup?
(Toxicology)
... USA remains its biggest consumer, the use of glyphosate has also increased in other countries. As such, from 1999 to 2010 glyphosate use in Germany increased by 100%, now being sprayed on nearly 40% of ...
Created on 23 August 2019
67. Comparison of the efficacy of several nutritional supplements on cancer and normal cells growth
(Other Aspects of Cancer)
... vary. Many contain single nutrients, while others contain combinations of vitamins, minerals, plant extracts and other nutritional components. The efficacy of such products will differ, but it is rarely, ...
Created on 23 August 2019
68. Vitamin D enhances anticancer effects of EGCG and a specific micronutrient combination in breast cancer cells
(Breast Cancer)
... to breast cancer in 2011. Current breast cancer therapies include localized surgery and radiation, as well as systemic treatments such as chemotherapy and hormone therapy.2 Although newer pharmaceutical ...
Created on 23 August 2019
69. Beneficial metabolic effects of Vitamin D on arterial wall cells in vitro
(Heart Disease)
... of coronary heart disease and its mortality.Vitamin D involvement in mitigating the pathogenesis and progression of CHD may occur at different levels, such as by regulation of renin-angiotensin system ...
Created on 23 August 2019
70. Different multi-nutrient formulations support calcification process in human bone cells
(Bone Health)
... connective tissues. Healthy bone metabolism depends on the proper function of different types of bone cells, such as osteoclasts which resorb (dissolve) the bone, osteoblasts that build the bone, osteocytes ...
Created on 23 August 2019
71. Cardiovascular Effects of Cyclical Dietary Vitamin C Withdrawal in Mice Deficient in Internal Synthesis of Vitamin C and producing human lipoprotein (a): Gulo(-/-); Lp(a)+
(Heart Disease)
... its continuous supplementation on metabolic factors related to cardiovascular health, such as lipid profile and vascular plaque development. Methods: Gulo (-/-); Lp (a)+ mice were subjected to 4 weeks ...
Created on 29 January 2019
72. A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells
(Female Reproductive Cancer)
... the nutrient mixture exhibited several characteristics  of  apoptosis  such  as  shrinkage  of  cytoplasm,  and  densely  staining  nuclei.  Both  early  and  late  apoptosis were detected moderately at ...
Created on 28 January 2019
73. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
(Other Aspects of Cancer)
... the limited economic burden of such a vaccine approach would allow its world-wide implementation towards the global control of cancer. Key words: cancer vaccine, melanoma B16FO, ...
Created on 23 January 2019
74. Programmed Cell Death in Renal Cancer Cell 786-0 by a Novel Nutrient Mixture by Down Regulating u-PA, MMPs, and Up Regulating TIMPs
(Kidney and Bladder Cancer)
... 2:1. Except for blood in the urine, other symptoms such as abdominal, back or flank pain, weight loss, and abnormal blood counts, are vague signs and symptoms that delay the diagnosis. Therefore, at ...
Created on 05 February 2018
75. Reciprocal cooperation of phytochemicals and micronutrients against typical and atypical forms of Borrelia spp.
(Lyme Disease)
... 28 combinations of phytochemicals such as polyphenols (baicalein, luteolin, rosmarinic acids), fatty acids (monolaurin, cis-2-decenoic acid), and micronutrients (ascorbic acid, cholecalciferol, and iodine). ...
Created on 23 June 2017
76. Composition of Plant-derived Compounds as an Alternative Approach to Lyme disease
(Scientific Presentations: Infectious Diseases)
... or additively to display higher efficacy compared to the individual components may serve as such an alternative for Lyme patients. Over 50 non-synthetic plant-derived active compounds and extracts were ...
Created on 20 June 2017
77. Modulation of MMP-2 and -9 Secretion by Cytokines, Inducers and Inhibitors in Human Melanoma A-2058 Cells
(Skin Cancer)
... aggressive cancer, causes the most skin cancer-related deaths, due to metastasis to other areas of the body, such as lymph nodes, lungs, liver, brain or bone. It is characterized by high levels of matrix ...
Created on 26 April 2017
78. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
(Head & Neck Cancers)
... on MMP-2. Our results showed that cytokines, mitogens and inhibitors modulated T-98G cell MMP-2 and MMP-9 expression, suggesting the clinical use of MMP inhibitors, particularly such potent and non-toxic ...
Created on 28 March 2017
79. Nutrient Synergy: A Novel Approach To Head And Neck Cancer (Chapter 1)
(Head & Neck Cancers)
... carcinoma (HNSCC), which develops in the mucous membranes of the oropharynx, nasopharynx, larynx and hypopharynx, can metastasize to other parts of the body, such as the lymph nodes or lungs leading to ...
Created on 28 March 2017
80. Cytokines, Inducers And Inhibitors Modulate Mmp-2 And Mmp‑9 Secretion By Human Fanconi Anemia Immortalized Fibroblasts
(Head & Neck Cancers)
... such potent and non-toxic ones as the NM and its component EGCG in the management of FA cancers.     Running title: Fanconi anemia fibroblast MMP modulation Keywords: matrix metalloproteinases, Fanconi ...
Created on 28 March 2017