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61. Cardiovascular Effects of Cyclical Dietary Vitamin C Withdrawal in Mice Deficient in Internal Synthesis of Vitamin C and producing human lipoprotein (a): Gulo(-/-); Lp(a)+
(Heart Disease)
... its continuous supplementation on metabolic factors related to cardiovascular health, such as lipid profile and vascular plaque development. Methods: Gulo (-/-); Lp (a)+ mice were subjected to 4 weeks ...
Created on 29 January 2019
62. A Novel Nutrient Mixture Induces Apoptosis in Human Ovarian and Cervical Cancer Cells
(Female Reproductive Cancer)
... the nutrient mixture exhibited several characteristics  of  apoptosis  such  as  shrinkage  of  cytoplasm,  and  densely  staining  nuclei.  Both  early  and  late  apoptosis were detected moderately at ...
Created on 28 January 2019
63. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
(Other Aspects of Cancer)
... the limited economic burden of such a vaccine approach would allow its world-wide implementation towards the global control of cancer. Key words: cancer vaccine, melanoma B16FO, ...
Created on 23 January 2019
64. Programmed Cell Death in Renal Cancer Cell 786-0 by a Novel Nutrient Mixture by Down Regulating u-PA, MMPs, and Up Regulating TIMPs
(Kidney and Bladder Cancer)
... 2:1. Except for blood in the urine, other symptoms such as abdominal, back or flank pain, weight loss, and abnormal blood counts, are vague signs and symptoms that delay the diagnosis. Therefore, at ...
Created on 05 February 2018
65. Reciprocal cooperation of phytochemicals and micronutrients against typical and atypical forms of Borrelia spp.
(Infectious Disease)
... 28 combinations of phytochemicals such as polyphenols (baicalein, luteolin, rosmarinic acids), fatty acids (monolaurin, cis-2-decenoic acid), and micronutrients (ascorbic acid, cholecalciferol, and iodine). ...
Created on 23 June 2017
66. Composition of Plant-derived Compounds as an Alternative Approach to Lyme disease
(Scientific-presentations: Infectious Diseases)
... or additively to display higher efficacy compared to the individual components may serve as such an alternative for Lyme patients. Over 50 non-synthetic plant-derived active compounds and extracts were ...
Created on 20 June 2017
67. Modulation of MMP-2 and -9 Secretion by Cytokines, Inducers and Inhibitors in Human Melanoma A-2058 Cells
(Skin Cancer)
... aggressive cancer, causes the most skin cancer-related deaths, due to metastasis to other areas of the body, such as lymph nodes, lungs, liver, brain or bone. It is characterized by high levels of matrix ...
Created on 26 April 2017
68. Nutrient Synergy: A Novel Approach To Head And Neck Cancer (Chapter 1)
(Head & Neck Cancers)
... carcinoma (HNSCC), which develops in the mucous membranes of the oropharynx, nasopharynx, larynx and hypopharynx, can metastasize to other parts of the body, such as the lymph nodes or lungs leading to ...
Created on 28 March 2017
69. Modulation of MMP-2 and MMP-9 secretion by cytokines, inducers and inhibitors in human glioblastoma T-98G cells
(Head & Neck Cancers)
... on MMP-2. Our results showed that cytokines, mitogens and inhibitors modulated T-98G cell MMP-2 and MMP-9 expression, suggesting the clinical use of MMP inhibitors, particularly such potent and non-toxic ...
Created on 28 March 2017
70. Cytokines, Inducers And Inhibitors Modulate Mmp-2 And Mmp‑9 Secretion By Human Fanconi Anemia Immortalized Fibroblasts
(Head & Neck Cancers)
... such potent and non-toxic ones as the NM and its component EGCG in the management of FA cancers.     Running title: Fanconi anemia fibroblast MMP modulation Keywords: matrix metalloproteinases, Fanconi ...
Created on 28 March 2017
71. Cooperation of Doxycycline with Phytochemicals and Micronutrients Against Active and Persistent Forms of Borrelia sp
(Infectious Disease)
... this aspect could advance our knowledge and help improve the efficacy of current approaches towards Borrelia sp. In this study, phytochemicals and micronutrients such as baicalein, luteolin, 10-HAD, ...
Created on 19 September 2016
72. Reciprocal Cooperation of Phytochemicals against Borrelia burgdorferi and Borrelia garinii
(Scientific-presentations: Infectious Diseases)
... defense, however, little is known about their anti-borrelaea reciprocal cooperation. To better understand this subject, we studied the efficacy of selected phytochemicals such as flavones and fatty acids ...
Created on 20 June 2016
73. Evaluation of Vitamin D3 and Vitamin C in Cooperation with Doxycycline against Borrelia burgdorferii and Borrlia garinii
(Scientific-presentations: Infectious Diseases)
... such cooperation, we studied the anti-bacterial efficacy of vitamin D3 and vitamin C (known for their antimicrobial activity) with doxycycline (one of the most frequently prescribed drugs for Lyme patients) ...
Created on 16 June 2016
74. New Non-synthetic Antibacterial Agents Challenging the Active and Persistent Forms of Borrelia ssp.
(Scientific-presentations: Infectious Diseases)
... on the administration of antibiotics. However, relapse often occurs when such treatment is withdrawn. One of the possible explanations for this clinical observation is the ability of Borrelia sp. to adapt ...
Created on 16 May 2016
75. A Nutrient Mixture Modulates Ovarian ES-2 Cancer Progression By Inhibiting Xenograft Tumor Growth And Cellular Mmp Secretion, Migration And Invasion
(Scientific Presentations: Cancer)
M.W. Roomi, M. Rath and A. Niedzwiecki Dr. Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050 Presented at: 55th Annual Meeting of ToxExpo, March 13-17, 2016, New Orleans, LA Published ...
Created on 17 April 2016
76. Activity of Phytochemicals against Biofilm of Borrelia burgdorferi and Borrelia garinii
(Scientific-presentations: Infectious Diseases)
... Poster #153 Background: Little is known about the activity of phytochemicals against biofilm of Borrelia sp. causing Lyme disease. To better understand the effects of such compounds, we studied the ...
Created on 17 April 2016
77. Efficacy of Doxycycline in Combination with Iodine against Biofilm of Borrelia burgdorferi and Borrelia garinii
(Scientific-presentations: Infectious Diseases)
... Poster #154   Background: The ability of Borrelia sp. to convert from their spirochete form into biofilm was observed. Such “self-defense” limits the antimicrobial action of many antimicrobial agents. ...
Created on 17 April 2016
78. Antiproliferative Effects of Antioxidants Using HTLV-1 Positive and Negative Malignant T-Cells
(Scientific-presentations: Infectious Diseases)
... is no proven therapy. Nutrients, such as ascorbic acid, lysine, and EGCG used individually and in combination with other nutrients (e.g., proline and N-Acetyl-L-Cysteine), were effective in inhibiting ...
Created on 17 April 2016
79. Borreliosis / Lyme Disease
(All Projects)
... may then transmit these bacteria to another host such as humans and/or animals by biting them. Some studies have shown that in order to transmit the spirochete an infected tick (also known as the black-legged ...
Created on 09 February 2016
80. Pleiotropic Effects of a Micronutrient Mixture on Critical Parameters of Bladder Cancer in Bladder Cancer, Etymology, Diagnosis and Treatment
(Kidney and Bladder Cancer)
... tissue as the common mechanisms used by all types of cancer cells for their development and spread. This can be achieved naturally through the synergistic effects of selected nutrients, such as lysine, ...
Created on 17 September 2015