- 61. Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions
- (Coronavirus)
- ... and curcumin displayed the highest binding with the receptor-binding domain of spike protein, inhibiting viral attachment to the human angiotensin-converting enzyme 2 receptor, and thus cellular entry ...
- Created on 22 June 2021
- 62. Polyunsaturated ω‑3 fatty acids inhibit ACE2‑controlled SARS‑CoV‑2 binding and cellular entry
- (Coronavirus)
- ... and eicosapentaenoic acid signifcantly block the entry of SARS-CoV-2. In addition, eicosapentaenoic acid showed higher efcacy than linolenic acid in reducing activity of TMPRSS2 and cathepsin L proteases, ...
- Created on 05 May 2021
- 63. Inhibition of ACE2 expression by Ascorbic acid alone and its combination with other natural compounds
- (Coronavirus)
- ... natural compounds were effective in lowering ACE2 cellular expression, with the highest inhibitory effects observed for baicalin (75%) and theaflavin (50%). Significantly, combinations of these and other ...
- Created on 17 February 2021
- 64. Scientific basis of micronutrient applications as an effective, safe, and affordable global public health strategy to help control the coronavirus pandemic
- (Coronavirus)
- ... and energy, among many other aspects. 2 This statement highlights the important, but often overlooked, fact that healthy nutrition supplying a full spectrum of micronutrients is the foundation of our immune ...
- Created on 02 February 2021
- 65. Immunological targeting of matrix metalloproteinase-9 as a novel approach to universal cancer vaccine: Characterization of anticancer antibodies efficacy in vitro
- (MMP)
- ... Current treatments are largely unsuccessful due to high toxicity. The most effective way to reduce global mortality from cancer is to block the initial stages of the disease, common to all types of cancer ...
- Created on 11 August 2020
- 66. Effective and safe global public health strategy to fight the COVID-19 pandemic: Specific micronutrient combination inhibits Coronavirus cell-entry receptor (ACE2) expression
- (Publications)
- ... the cause of the common flu, coronaviruses were frequently found inside the endothelial cells and COVID-19 was associated with a nine times higher frequency of microscopic blood clots (microthrombi) along ...
- Created on 02 July 2020
- 67. Scientific Breakthough Towards Natural Control of the Pandemic
- (Publications)
- ... frequently found inside the endothelial cells and COVID-19 was associated with a nine times higher frequency of microscopic blood clots (microthrombi) along the blood vessel walls (Ackermann 2020). A ...
- Created on 29 June 2020
- 68. Matrix metalloproteinases-9 as a promising target for anti-cancer vaccine: inhibition of melanoma tumor growth in mice immunized with syngeneic MMP-9 peptides
- (MMP)
- ... a challenge. Current treatments are largely unsuccessful due to high toxicity. The most effective way to reduce global mortality from cancer is to block the initial stages of the disease, common to all ...
- Created on 08 February 2020
- 69. Progress of Tumor Growth and Metastasis after Inoculation of B16FO Melanoma Cells in Kidney of Female Nude Mice Is Inhibited by a Novel Nutrient Mixture
- (Skin Cancer)
- ... deaths. Melanoma is a serious cancer that metastasizes to other areas of the body, including the lungs, liver, brain, bones, or lymph nodes. Currently used cancer therapies are ineffective with a high ...
- Created on 08 February 2020
- 70. Anti-borreliae Efficacy of Volatile and Non-volatile Organic Oils and Lipids
- (Scientific Presentations: Infectious Diseases)
- ... 90% of eradication mark. Based on the obtained results, volatile oils were more potent than non-volatile oils and lipids. Also, among all tested agents, chamomile oil and erucic acid seem to have the highest ...
- Created on 07 December 2019
- 71. Anti-borreliae efficacy of selected organic oils and fatty acids
- (Lyme Disease)
- ... Among all tested oils, Bay leaf oil and Cassia oil, with their major components eugenol and cinnamaldehyde, seem to have the highest anti-borreliae efficacy. This article is protected by copyright. All ...
- Created on 07 December 2019
- 72. Sathvika Gopalasetty
- (Future Scientist)
- Sathvika Gopalasetty is currently a junior in Monta Vista High School in Cupertino, California with an immense interest in research and biology. Millions across the world, including several of her own ...
- Created on 20 September 2019
- 73. Vitamin C in Health: Scientific focus on its anti-cancer efficacy
- (Other Aspects of Cancer)
- ... of vitamin C is much more effective in achieving higher plasma levels, compared to oral administration, making the former the preferred means of administering Vitamin C to achieve sustainable therapeutic ...
- Created on 23 August 2019
- 74. Diabetes in Children and the Role of Micronutrients
- (Diabetes)
- ... This disease, characterized by impaired glucose metabolism and abnormally high blood glucose levels, has serious negative health consequences in young organisms, many of which surface later in life. In ...
- Created on 23 August 2019
- 75. Phytonutrients inhibit fibrosarcoma and melanoma cell growth and invasion
- (Skin Cancer)
- ... carcinogenesis is gaining increasing importance, since scientific evidence shows that high consumption of fruits and vegetables are associated with a reduced risk of various cancers. PB, which is composed ...
- Created on 23 August 2019
- 76. Progress of Tumor Growth and Metastasis After Inoculation of B16FO Melanoma Cells in Kidney of Female Nude Mice Is Inhibited by a Novel Nutrient Mixture
- (Skin Cancer)
- ... nodes. Currently used cancer therapies are ineffective with a high degree of toxicity and patient mortality. Thus, any successful treatment for melanoma must target metastasis. Methods: We studied ...
- Created on 08 May 2019
- 77. A Novel Nutrient Mixture Induces Apoptosis in Human Mesothelioma Cells (MSTO-211H) via Activation of Caspases
- (Lung Cancer)
- ... Malignant mesothelioma is a highly aggressive and fatal cancer of older people. Consistently associated with asbestos exposure, mesothelioma is diagnosed when it is extensively metastasized and it has ...
- Created on 08 May 2019
- 78. Chlorophyllin Suppresses Growth, MMP Secretion, Invasion and Cell Migration of Fibrosarcoma Cell LineHT1080
- (Sarcomas)
- ... and highly malignant cancer of connective tissue with the lung being the most common site of metastasis. Surgery, chemotherapy, and radiation are the mainstay of treatments, yet the prognosis is very poor. ...
- Created on 08 February 2019
- 79. Scientific evaluation of dietary factors in cancer
- (Other Aspects of Cancer)
- ... many food additives, pesticide residues and high consumption of charbroiled meat, nitrites, salt, animal fat and trans fatty acids have been associated with increased cancer risk. Most studies with micronutrients ...
- Created on 08 February 2019
- 80. Peptide vaccines directed against human Metalloproteinases (MMPs) with anti-tumor efficacy in vitro and in vivo
- (Other Aspects of Cancer)
- ... but on average was even more pronounced. The highest reduction of tumor volume compared to control was 88% achieved with a vaccine derived from the human MMP-2 oligopeptide, followed by a reduction of ...
- Created on 23 January 2019