Blood cancers

Nutrient Mixture Inhibits in vitro and in vivo Growth of Human Acute Promyelocytic Leukemia HL-60 Cells

MW Roomi, NW Roomi, B Bhanap, A Niedzwiecki, M Rath;                                                        

Exp Oncol. 2011;33(4):212-215

Abstract:

Aim:Untreated acute promyelocytic leukemia is the most malignant form of acute leukemias, with median survival of less than one month. We investigated in vitro and in vivo synergistic effects of a nutrient mixture (NM) containing ascorbic acid, lysine, proline, and green tea extract, on acute promyelocytic leukemia HL-60 cells.

Read more: Nutrient Mixture Inhibits in vitro and in vivo Growth of Human Acute Promyelocytic Leukemia HL-60 Cells

Antineoplastic effect of nutrient mixture on Raji and Jurkat T cells: the two highly aggressive non Hodgkin’s lymphoma cell lines

MW Roomi, BA Bhanap, NW Roomi, A. Niedzwiecki and M. Rath

Experimental Oncology 2009; 31(3): 149-155.

Abstract:

Non-Hodgkin lymphomas incidence has increased more than 70% in last 25 years. Aggressiveness, higher relapse rate, and treatment complications pose significant barriers. Decreased food intake and side effects of treatments make cancer patients vulnerable to deficiency of essential nutrients such as vitamin C, lysine, and proline leading to the formation of weak extra cellular matrix susceptible to easy breakdown by matrix metalloproteinase enzymes. Inhibition of these enzymes has shown promise in stopping metastasis.…

Read more: Antineoplastic effect of nutrient mixture on Raji and Jurkat T cells: the two highly aggressive non Hodgkin’s lymphoma cell lines