M.W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki
Oncology Division, Dr. Rath Research Institute,1260 Memorex Drive, Santa Clara, CA 95050
Nutraceuticals – Efficacy, Safety and Toxicity, ed. R.C. Gupta, Elsevier 2016, pp 135-144
Hemangiomas are the most common congenital vascular and benign tumor in infants and children. Most hemangiomas do not cause major symptoms to require intervention, however, the larger hemangiomas have tendency to bleed and may require surgical removal. Experimental studies have demonstrated the role of urokinase plasminogen activator (u-PA), especially cell surface u-PA, as an initiator of extra-cellular matrix proteolysis and associated tumor cell invasion.