Roomi MW, Kalinovsky T, Niedzwiecki A, Rath M
Breakthroughs in Melanoma Research, ed. Y. Tanaka, In Tech Publisher, 2011, Ch 26, pp 559-574
Consumption of a plant-based diet has been associated with prevention of the development and progression of cancer. We have developed strategies to inhibit cancer development and its spread by targeting common mechanisms used by all types of cancer cells that decrease stability and integrity of connective tissue. Our approach to strengthening of collagen and connective tissue compromised in cancer metastasis , tumor growth and angiogenesis has been based on using specific natural components, among them lysine, proline, ascorbic acid and green tea extract (NM). We have documented synergistic effects of this micronutrient mixture and its effectiveness in controlling key mechanisms of cancer in vivo and in vitro in a wide variety of cancer cell lines.