Although COVID-19 has now become an endemic and is less severe, flu and COVID-19 remain a concern due to the continuous mutations of these viruses. Vaccinations have only limited efficacy against the most recent variants. Hospitals have brought back the mask requirements due to an increase in the infection rates and the health officials expect a significant rise in respiratory illnesses and admissions during the winter months. The latest variants of SARS-CoV-2 (JN.1) caused almost half of the COVID-19 cases around the holidays. In the past couple of years, it has also been observed that COVID-19 is not only a cause of temporary respiratory illness, but it triggers a new and chronic illness. The so called “long Covid” could be more debilitating for previously healthy people. It can last for weeks even years after the infection and it can be manifested as cardiovascular problems, cognitive impairment, brain fog, concentration and memory issues, nerve pains, and others.