Bone cancer is the cancer originating primarily from the bone and its surrounding tissue. However, the most common form of cancer in the bones is from metastasis from another primary cancer at a different organ. Osteosarcoma is the most common primary bone cancer followed by chondrosarcoma, Ewing’s sarcoma, fibrosarcoma and others.
Worldwide, kidney cancer is one of the 10 most common cancers in both men and women. The American Cancer Society estimates 63,990 new cases of kidney cancer will be diagnosed in the US in 2017. Kidney tumors can be either benign (non-cancerous) or malignant (cancerous) and since they tend to grow quickly without any specific symptoms, they are usually removed before any diagnostic biopsy is done. Males tend to get kidney cancer twice as often as females. Common risk factors for kidney cancer include smoking, obesity, and exposure to chemicals like benzene, asbestos, and certain pesticides. Being African American or a family history of hypertension, lymphoma or kidney cancer, and certain genetic conditions further increase the risk of developing kidney cancer.
Head and neck cancers are a group of tumors originating from several areas above the collarbone. They include cancers of the larynx, salivary glands, tongue, thyroid, and nasopharyngeal area. Annually there are 60,000 new cases of head and neck squamous cell carcinoma (HNSCC) in the US, and more than 13,000 deaths. Squamous cells are a type of cells found in the outer layer of the skin and in the mucous membranes and include the cells lining airways and intestines.
The biggest risk factor for head and neck cancers include tobacco use and smoking (this includes the smokeless tobacco), and alcohol - all of which are highly preventable causes. Additionally, sun exposure, and occupational exposure to substances like chromium, radium, leather, and wood dust can also increase the risk of developing HNSCC. Hence, the ears, nose, and throat happen to be the most common affected areas.
Ovarian Cancer is the fifth leading cause of cancer deaths in the USA, and is the deadliest of gynecological cancers in women. According to the 2016 estimates of the American Cancer Society, 22,280 women will be diagnosed with ovarian cancer in the United States and 14,240 women will die from this disease. The main reason for such high death rate is that ovarian cancer is often diagnosed when the disease has already progressed. Unfortunately, there are no specific symptoms pointing to ovarian cancer. A woman can have an array of vague symptoms such as dull abdominal pain, feeling of fullness or bloating, changed bowel habits, indigestion, loss of appetite and weight loss. Sometimes, an abdominal mass may also be present. This non-specificity of symptoms helps explain why the majority of women are diagnosed when the cancer has already spread to the pelvis, abdominal organs, the liver and the lungs.
Our last issue of our Health Science News Page focused on polyphenols, which are the nutrient compounds present in various plants that help in protecting plants from insects, diseases, pollutants, and damage from ultraviolet rays. In Part 1 we discussed a few of the important and most researched polyphenols - specifically quercetin, curcumin, green tea extract, and resveratrol - and their actions and functions in the human body.
Phytonutrients are natural components of plants with important functions such as protecting plants from insects, diseases, draught, ultraviolet rays, and pollutants. The best known phytonutrients are the polyphenols, carotenoids, flavonoids, catechins, and isoflavones. There are various sub-classifications of phytonutrients which include ligans, phenolic acids, and indoles. Flavones are present in vegetables such as parsley and celery, and flavolones are present in tomatoes and other citrus fruits. Catechins are present in fruits, red wine, green tea and chocolate. Ligans are found in various legumes, cereals, grains, and flax seed. In addition to protecting plants against various pathogenic organisms and ultraviolet rays, polyphenols also act as antioxidant and anti-inflammatory agents.
Apoptosis, also referred to as “programmed cell death,” or “cell suicide,” originates from a combination of Greek words that can be loosely translated as “falling off.” Apoptosis is a physiological process essential for the development and function of the human body and other multicellular organisms. Millions of cells routinely die in the bone marrow and intestines every hour. It is estimated that approximately 50-70 billion cells die due to apoptosis every day in an average human adult.
Cancer of the urinary bladder is the fourth most common cause of cancer in men. Most bladder cancer patients tend to be older men over the age of 60. The American Cancer Society estimates that in 2015, approximately 74,000 new cases of bladder cancer will be diagnosed in the US.
Kidneys are a part of the urinary system. A pair of fist-sized kidneys is located in the flanks on either side of the vertebral column. The main function of the kidneys is to form urine by removing water and waste products from the body. Urine is then stored in the urinary bladder to be later excreted.
Skin cancer is the most common of all types of cancers. While melanoma is the most feared skin cancer, non-melanoma skin cancers are far more common. The American Cancer Society estimates 73,000 Americans will be diagnosed with melanoma in 2015; however, there will be 3.5 million new cases of non-melanoma cancers.