Sarcomas are cancers of connective tissue such as hard tissue (bones), soft tissue (muscles) and tendons. Although sarcomas are uncommon at any age, they are relatively frequent in children. Every year in the USA approximately 1500-1700 children and young people under the age of 20 are diagnosed with bone and soft tissue sarcomas. Sarcomas are one of the most life-threatening cancers in children, and survival ranges from 59%-68% depending on factors such as age, other risks (i.e., tumor location, gender, environment, genetics), prescription medications and other drugs, etc.