| July 25, 2008
Vitamin Supplementation Found to Benefit Hemodialysis Patients
In a retrospective study involving 83 patients undergoing hemodialysis (3 x 4 hr/weekly), patients treated with erythropoietin (EPO) who also received supplementation with pyridoxine (20 mg/d), folic acid (10 mg/week), and vitamin C (60 mg/d), were found to have increases in blood hemoglobin (from 100 to 110 g/L), erythrocyte vitamin B6 (from 30.4 to 16.4%), erythrocyte folic acid (from 343.3 to 734.5 ng/mL), and plasma vitamin C (from 63.5 to 88.3 micromol/L). When vitamin E-coated dialyzer was used for 3 months, erythrocyte vitamin E increased from 6.7 to 7.4 micromol/L and plasma malondialdehyde decreased from 2.8 to 2.2 micromol/L. Prior to supplementation, hemodialysis patients were found to have low levels of these vitamins; after supplementations, these levels normalized. The authors conclude, "Adequate supplementation of above mentioned vitamins led to increased quality of life in hemodialysis patients from some clinical points of view."
Reference: "Vitamins and quality of life in hemodialysis patients," Mydlik M, Derzsiova K, et al, J Nephrol, 2008; Suppl 13:S129-33. (Address: Nephrology Clinic, Medical School of P.J. Safárik University and Logman a.s., Rastislavova, Kosice, Slovak Republic).
Source: VitaSearch
Source: http://www.vitasearch.com/get-clp-summary/37504
Comments:
Oxidative stress is already increased in hemodialysis patients leading to significant changes in kidney function. Therefore, antioxidants such as vitamin C are essential, however they are categorically avoided in the treatment of kidney diseases. Conventional medicine usually tries to avoid vitamin C, as it is blamed to promote kidney stones (urolithiasis) and further deteriorates kidney function. In fact, there are several studies proving the opposite. This is one of the examples of a fairly large study reiterating the benefits of multi-nutrient supplementation in patients with severe kidney dysfunction requiring hemodialysis.
More than a decade ago, Dr. Rath's research pioneered the new concept of nutrient synergy and proved its importance in diabetes, diabetic complications and other diseases. Mega doses of any single nutrient is not as beneficial as is the combination of specific nutrients in specific proportions. This study has also effectively used the same concept of nutrient combination and proven the efficacy of vitamin C and other vitamins in severe kidney dysfunction. You can read more about Dr. Rath's research at www.drrathresearch.org and the concept of nutrient synergy at www.cellularhealthtraining.org
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