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March 30, 2007

Nutrient Combo May Curb Hearing Loss

Mix of Magnesium and Vitamins A, C, E May Help Prevent Noise-Induced Hearing Loss

By Miranda Hitti
WebMD Medical News

Reviewed By Louise Chang, MD

March 30, 2007 -- Taken together, magnesium and vitamins A, C, and E may help protect the ears from noise-induced hearing loss.

So say scientists including Colleen Le Prell, PhD, of the University of Michigan's Kresge Hearing Research Institute.

So far, Le Prell's team has only tested the nutrient mixture against noise-induced hearing loss in guinea pigs.

But the results of those guinea pig tests provide a "compelling rationale for human trials," the researchers write.

Their report appears in Free Radical Biology & Medicine.

The researchers studied four groups of male guinea pigs. Each group got one of the following treatments once daily for six days:

  • Magnesium and vitamins A, C, and E
  • Vitamins A, C, and E without magnesium
  • Magnesium only
  • Salt water (placebo)

One hour after the first treatment, the guinea pigs were exposed to 120 decibels of noise for five consecutive hours.

To put that in perspective, 120 decibels is as loud as an ambulance siren, according to the National Institute on Deafness and Other Communication Disorders (NIDCD).

Prolonged exposure to any noise above 85 decibels can cause gradual hearing loss, notes the NIDCD. Wearing earplugs or other special ear muffs may help protect hearing in noisy settings.

The guinea pigs were only exposed to the noise once. They got daily doses of their assigned treatment for the five days following noise exposure.

Five days after noise exposure, the guinea pigs took hearing tests and had their ears examined.

The guinea pigs that got the combination treatment of magnesium and vitamins A, C, and E had the least amount of noise-induced hearing loss and ear damage.

The guinea pigs in the three other groups had no hearing benefits. Magnesium and vitamins A, C, and E may work best together to prevent noise-induced hearing loss, the researchers write.

The study doesn't show whether the treatment given before noise exposure was more important than the treatments given after noise exposure.

The researchers speculate that the nutrient combination might reduce hearing loss even when it's only given after exposure to noise, but this study didn't test that theory.

The University of Michigan has applied for patents for the nutrient combination's use in preventing noise-induced hearing loss.

One of the researchers -- Josef Miller, PhD of the University of Michigan and the Center for hearing and Communication at Sweden's Karolinska Institute -- is the founder and chairman of a company called OtoMedicine, Inc., which is developing the vitamin and magnesium treatment.

Source: www.medicinenet.com

Comments:
Noise Induced hearing loss is the second most common cause of hearing impairment after aging. With approximately 30 million Americans having some degree of hearing impairment, 10 million suffer due to preventable causes such as excessive noise exposure. Yet there is no specific treatment available other than hearing aides. This study proves that use of nutrients is one more avenue that could maintain quality of life of many of these people without any side effects.

Researchers at Dr. Rath's Research Institute have already proved that combination of these antioxidants with other nutrients significantly improve hearing loss in tinnitus. The principle of nutrient synergy is an innovative approach used by Dr. Rath stresses the importance of combinations of nutrients rather than single nutrient. Through such an approach, mega doses of individual nutrients can be avoided with better results. This study further confirms those findings. Please read about Dr. Rath's studies under “clinical studies” on www.drrathresearch.org

 

 
       
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