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March 20, 2008

Treanda Treats Rare Cancer

THURSDAY, March 20 (HealthDay News) — The Cephalon drug Treanda (bendamustine hydrochloride) has been approved by the U.S. Food and Drug Administration to treat chronic lymphocytic leukemia, a rare cancer that affects the blood and bone marrow.

CLL is expected to strike some 15,000 people in the United States this year, according to American Cancer Society estimates provided by the drugmaker.

In a trial of 301 patients that compared Treanda to an already approved chemotherapy drug, Treanda recipients had better response rates and longer progression-free survival, Cephalon said in a statement.

Treanda, expected to hit the U.S. market in April, works by damaging the DNA in cancer cells, causing these cells to die. Cephalon said the treatment was granted orphan drug status by the FDA, which offers companies exclusive marketing rights in return for drugs developed for rare diseases.

SOURCE: www.medicinenet.com

Comment:
Chronic lymphocytic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). It is a disease that occurs in older adults and usually worsens slowly. The disease progression can sometimes be so slow that immediate treatment is also not indicated. Due to this background, this drug is granted special “orphan drug” status with exclusive marketing rights and accelerated approval because it is developed for a rare disease.

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