Assuming cancer is required, the following results were found.

  • In Vitro Modulation of MMP-2 and MMP-9 Secretion by Cytokines, Inducers, and Inhibitors in Head and Neck Squamous Carcinoma Cells (FaDu) and Tongue Carcinoma Cells (SCC-25)

    M W Roomi, B Bhanap, A Niedzwiecki and M Rath J Otolaryngol Rhinol 2017, 3:029; Vol 3 | Issue 1 Abstract: Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with poor prognosis. Matrix metalloproteinases (MMPs), specifically, MMP-2...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/529-in-vitro-modulation-of-mmp-2-and-mmp-9-secretion-by-cytokines-inducers-and-inhibitors-in-head-and-neck-squamous-carcinoma-cells-fadu-and-tongue-carcinoma-cells-scc-25?Itemid=435
  • Effect Of A Nutrient Mixture On Fanconi Anemia Fibroblast And Normal Human Dermal Fibroblast: A Comparison

    a fatal heterogeneous autosomal recessive disorder, characterized by progressive bone marrow failure, congenital defect and cancer predisposition. Cell culture from FA fibroblast (FAF) displays certain abnormalities as compared to normal human dermal...

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/484-effect-of-a-nutrient-mixture-on-fanconi-anemia-fibroblast-and-normal-human-dermal-fibroblast-a-comparison?Itemid=435
  • Anticancer Effects of a Specific Mixture of Nutrients in Multidrug Resistant Human Uterine Sarcoma Cell Line MES-SA/Dx5 and in Drug Sensitive MES-SA Cell Line

    ascorbic acid and green tea extract (NM) has demonstrated a broad spectrum of antitumor activity against a number of cancer cell lines. In this study, our main objective was to investigate the comparative effects of NM on anticancer parameters such as...

    http://www.drrathresearch.org/component/content/article/137-female-reproductive-cancer/248-anticancer-effects-of-a-specific-mixture-of-nutrients-in-multidrug-resistant-human-uterine-sarcoma-cell-line-mes-sa-dx5-and-in-drug-sensitive-mes-sa-cell-line?Itemid=435
  • Suppression of metastasis of intratesticular inoculation of B16FO melanoma cells by a novel nutrient mixture in male athymic nude mice

    Medicine 2012; 4: 775-780 Abstract: Metastasis, commonly to the lung, is the major cause of death from testicular cancer. We studied the effect of a novel nutrient mixture (NM) containing ascorbic acid, amino acids and green tea extract on inhibition of...

    http://www.drrathresearch.org/component/content/article/110-skin-cancer/238-suppression-of-metastasis-of-intratesticular-inoculation-of-b16fo-melanoma-cells-by-a-novel-nutrient-mixture-in-male-athymic-nude-mice?Itemid=435
  • In vitro inhibition of matrix metalloproteinases, invasion and growth of Fanconi anemia human FANCA and FANCC lymphoblasts by nutrient mixture

    Oncol.2014;36(3):212-4. Abstract: Aim: Fanconi anemia is a rare genetic disorder with high propensity for development of cancers, such as aplastic anemia, leukemia and head and neck cancers. Collagen digesting matrix metalloproteinase (MMP) enzymes have...

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/521-in-vitro-inhibition-of-matrix-metalloproteinases-invasion-and-growth-of-fanconi-anemia-human-fanca-and-fancc-lymphoblasts-by-nutrient-mixture?Itemid=435
  • In vivo and in vitro antitumor effects of nutrient mixture in murine leukemia cell line P-388

    containing lysine, proline, ascorbic acid, green tea extract and other nutrients is formulated to target key pathways in cancer progression.

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/524-in-vivo-and-in-vitro-antitumor-effects-of-nutrient-mixture-in-murine-leukemia-cell-line-p-388?Itemid=435
  • Antineoplastic effect of nutrient mixture on Raji and Jurkat T cells: the two highly aggressive non Hodgkin’s lymphoma cell lines

    rate, and treatment complications pose significant barriers. Decreased food intake and side effects of treatments make cancer patients vulnerable to deficiency of essential nutrients such as vitamin C, lysine, and proline leading to the formation of...

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/525-antineoplastic-effect-of-nutrient-mixture-on-raji-and-jurkat-t-cells-the-two-highly-aggressive-non-hodgkin-s-lymphoma-cell-lines?Itemid=435
  • Down regulation of u-Pa by a nutrient mixture In hemangioma (eoma) cells by inducing Caspase-dependent apoptosis

    M.W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki Oncology Division, Dr. Rath Research Institute,1260 Memorex Drive, Santa Clara, CA 95050 Nutraceuticals – Efficacy, Safety and Toxicity, ed. R.C. Gupta, Elsevier 2016, pp 135-144 Abstract: Hemangiomas...

    http://www.drrathresearch.org/component/content/article/114-other-aspects-of-cancer/530-down-regulation-of-u-pa-by-a-nutrient-mixture-in-hemangioma-eoma-cells-by-inducing-caspase-dependent-apoptosis?Itemid=435
  • Inhibition of human neuroblastoma cell line SK-N-MC in vivo and in vitro by a novel nutrient mixture

    Drive, Santa Clara, CA 95050 Oncology Reports 2013; 29: 1714-1720 Abstract Neuroblastoma, a peripheral nervous system cancer that can be highly invasive and metastatic, accounts for 8-10% of all solid childhood tumors in children under the age of 15...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/245-inhibition-of-human-neuroblastoma-cell-line-sk-n-mc-in-vivo-and-in-vitro-by-a-novel-nutrient-mixture?Itemid=435
  • Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human glioblastoma cell lines

    metalloproteinase (MMP)-2 and -9 secretions that degrade the extracellular membrane (ECM) and basement membrane, allowing cancer cells to spread to distal organs. Proteases play a key role in tumor cell invasion and metastasis by digesting the basement...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/244-modulation-of-u-pa-mmps-and-their-inhibitors-by-a-novel-nutrient-mixture-in-human-glioblastoma-cell-lines?Itemid=435
  • Marked inhibition of growth and invasive parameters of head and neck squamos carcinoma fadu by a nutrient mixture

    M.W. Roomi, N.W. Roomi, T. Kalinovsky, M. Rath, A. Niedzwiecki Integrative Cancer Therapies 2009; 8(2): 168-176 Head and neck squamous cell carcinomas (HNSCC) are known for their aggressive growth and propensity to metastasize. We investigated the...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/251-marked-inhibition-of-growth-and-invasive-parameters-of-head-and-neck-squamos-carcinoma-fadu-by-a-nutrient-mixture?Itemid=435
  • Inhibition of Glioma Cell Line A-172 MMP Activity and Cell Invasion In Vitro by a Nutrient Mixture

    M.W. Roomi, V. Ivanov, T. Kalinovsky, A. Niedzwiecki, M. Rath Medical Oncology 2007, 24(2): 231-238 Standard multimodality therapy of gliomas is associated with poor patient survival and significant toxicity. Abnormal expression of matrix...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/252-inhibition-of-glioma-cell-line-a-172-mmp-activity-and-cell-invasion-in-vitro-by-a-nutrient-mixture?Itemid=435
  • In Vivo and In Vitro Effect of a Nutrient Mixture of Chemopreventive Agents on Human Hepatocarcinoma Cells

    Exp Oncol 2010, 32: 84-91 Abstract Purpose : Long-term survival of patients with hepatocellular carcinoma (HCC), a common cancer worldwide, remains poor, due to metastasis and recurrence. We investigated the effect of a novel nutrient mixture (NM) of...

    http://www.drrathresearch.org/component/content/article/103-gastrointestinal-cancers/249-in-vivo-and-in-vitro-effect-of-a-nutrient-mixture-of-chemopreventive-agents-on-human-hepatocarcinoma-cells?Itemid=435
  • In Vitro and In Vivo Inhibition of Human Fanconi Anemia Head and Neck Squamous Carcinoma by a Phytonutrient Combination

    M.W. Roomi, T. Kalinovsky, N.W. Roomi, A. Niedzwiecki and M. Rath Dr. Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050 International Journal of Oncology 2015 DOI: 10.3892/ijo.2015.2895 Abstract: Head and neck squamous cell carcinoma...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/243-in-vitro-and-in-vivo-inhibition-of-human-fanconi-anemia-head-and-neck-squamous-carcinoma-by-a-phytonutrient-combination?Itemid=435
  • Antineoplastic activity of a nutrient mixture in Y-79 malignant retinoblastoma cells

    Roomi MW, Roomi N, Bhanap B, Niedzwiecki A, Rath M Oncol Rep. 2013; 29(1):29-33 Abstract: Retinoblastoma is one of the most common ocular malignancies in children under the age of six. Occasionally, retinoblastoma metastasizes to extraocular organs...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/519-antineoplastic-activity-of-a-nutrient-mixture-in-y-79-malignant-retinoblastoma-cells?Itemid=435
  • A Nutrient Mixture Inhibits Glioblastoma Xenograft U-87 Mg Growth In Male Nude Mice

    M.W. Roomi, T. Kalinovsky, A. Niedzwiecki and M. Rath Dr. Rath Research Institute, 1260 Memorex Drive, Santa Clara, CA 95050 Experimental Oncology 38(1):1-3, 2016 Abstract: Brain tumors are highly aggressive tumors characterized by secretions of high...

    http://www.drrathresearch.org/component/content/article/113-head-neck-cancers/485-a-nutrient-mixture-inhibits-glioblastoma-xenograft-u-87-mg-growth-in-male-nude-mice?Itemid=435
  • Visit Our Lab

    we investigate how specific micronutrient synergies can affect cellular mechanisms involved in the growth and spread of cancer, the development and progression of cardiovascular disease, immune deficiencies, viral infections and other health aspects. We...

    http://www.drrathresearch.org/research/visit-our-lab
  • Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines

    by high levels of matrix metalloproteinase (MMP)-2 and -9 secretions that degrade the ECM and basement membrane, allowing cancer cells to spread to distal organs. Proteases play a key role in tumor cell invasion and metastasis by digesting the basement...

    http://www.drrathresearch.org/component/content/article/104-sarcomas/259-modulation-of-u-pa-mmps-and-their-inhibitors-by-a-novel-nutrient-mixture-in-adult-human-sarcoma-cell-lines?Itemid=435
  • Mechanistic aspects of apoptosis induction by L-lysine in both HTLV-1-positive and -negative cell lines

    S. Harakeh, M. Diab-Assaf, K. Abu-El-Ardat, A. Niedzwiecki, M. Rath Chemico-Biological Interactions 2006, 164: 102-114 Abstract : The retrovirus human T-cell lymphotrophic virus type-1 (HTLV-1) causes adult T-cell leukemia (ATL), which remains with no...

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/270-mechanistic-aspects-of-apoptosis-induction-by-l-lysine-in-both-htlv-1-positive-and-negative-cell-lines?Itemid=435
  • Nutrient Mixture Inhibits in vitro and in vivo Growth of Human Acute Promyelocytic Leukemia HL-60 Cells

    MW Roomi, NW Roomi, B Bhanap, A Niedzwiecki, M Rath; Exp Oncol. 2011;33(4):212-215 Abstract: Aim:Untreated acute promyelocytic leukemia is the most malignant form of acute leukemias, with median survival of less than one month. We investigated in vitro...

    http://www.drrathresearch.org/component/content/article/112-blood-cancer/523-nutrient-mixture-inhibits-in-vitro-and-in-vivo-growth-of-human-acute-promyelocytic-leukemia-hl-60-cells?Itemid=435

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